Now showing items 1-4 of 4
Chronic defensiveness and neuroendocrine dysfunction reflect a novel cardiac troponin T cut point: the SABPA study
Background Sympatho-adrenal responses are activated as an innate defense coping (DefS) mechanism during emotional stress. Whether these sympatho-adrenal responses drive cardiac troponin T (cTnT) increases are unknown. ...
Therapeutic potential of selectively targeting the α2c-adrenoceptor in cognition, depression, and schizophrenia: new developments and future perspective
(Frontiers Media, 2017)
α2A- and α2C-adrenoceptors (ARs) are the primary α2-AR subtypes involved in central nervous system (CNS) function. These receptors are implicated in the pathophysiology of psychiatric illness, particularly those associated ...
Methylene blue and its analogues as antidepressant compounds
Methylene Blue (MB) is considered to have diverse medical applications and is a well-described treatment for methemoglobinemias and ifosfamide-induced encephalopathy. In recent years the focus has shifted to MB as an ...
Ketamine and aminoguanidine differentially affect Bdnf and Mtor gene expression in the prefrontal cortex of adult male rats
The rapid and sustained antidepressant properties of ketamine provide evidence of the importance of the glutamatergic system in the neurobiology of depression. The antidepressant-like effects of ketamine are dependent on ...