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Exploring the link between cardiovascular reactivity and end–organ damage in African and Caucasian men: the SABPA study
(Oxford University Press, 2013)
BACKGROUND Heart failure in the African population is reaching alarming levels. Increased afterload as a result of increased vasoconstriction during stress may lead to impaired ventricular function and stroke volume (SV) ...
Extracellular matrix biomarker, Fibulin–1 and Its association with Soluble uPAR in a Bi-ethnic South African population: the SAfrEIC study
(Elsevier, 2015)
Background
Fibulin-1 and soluble urokinase-type plasminogen activator receptor (suPAR) emerged as mediators in the development of sclerotic disease. SuPAR along with C-reactive protein (CRP) and albumin delineate ...
Cornell product relates to albuminuria in hypertensive black adults independently of blood pressure: the SABPA study
(Elsevier, 2015)
Evidence of the relationship between left ventricular hypertrophy and urinary albumin excretion is contradictory and limited in black adults in whom hypertensive heart disease is common. We aimed to investigate the ...
Low testosterone and hyperkinetic blood pressure responses in a cohort of South African men: the SABPA study
(Taylor & Francis, 2013)
Hypertension (HT) and the metabolic syndrome are major problems in Africa. The role of sex hormones in the cardiovascular profile of black Africans in South Africa has not been studied. Our objective was to study the ...
South African and international reference values for lung function and its relationship with blood pressure in Africans
(Elsevier, 2015)
Background
In South Africa respiratory diseases are highly prevalent, with cardiovascular disease being a manifestation. However, international reference values for lung function are commonly used, which may not be ...
The relationship of nitric oxide synthesis capacity, oxidative stress, and albumin-to-creatinine ratio in black and white men: the SABPA study
(Springer, 2016)
Inadequate substrate availability and increased
nitric oxide synthase inhibitor levels attenuate nitric oxide
(NO) synthesis, whereas increased vascular oxidative
stress may lead to inactivation of NO. We compared
markers ...
Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians
(BioScintifica, 2010)
Objective
Alarming increases in hypertension and type 2 diabetes among Africans accentuate the need to identify factors that could serve as targets for prevention or treatment. In Caucasian populations, asymmetric ...
Serum calcium revisited: associations with 24-h ambulatory blood pressure and cardiovascular reactivity in Africans
(Nature, 2010)
Sub-Saharan Africans face an increasing burden of hypertension. Although controversial, recent experimental evidence strongly suggests that serum calcium contributes to elevated blood pressure through increased vascular ...
Retinal vessel caliber and caliber responses in true normotensive black and white adults: the African-PREDICT study
(Elsevier, 2020)
Purpose
Globally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis ...
Drink types unmask the health risks associated with alcohol intake: prospective evidence from the general population
(Elsevier, 2020)
Background & aims
Uncertainty still exists on the impact of low to moderate consumption of different drink types on population health. We therefore investigated the associations of different drink types in the form of ...