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Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study
(Elsevier, 2015)
Background: Alcohol consumption is proposed to be the third most important modifi able risk factor for death and disability. However, alcohol consumption has been associated with both benefi ts and harms, and previous ...
Prediction of 24-hour sodium excretion from spot urine samples in South African adults: a comparison of four equations
(Nature, 2020)
Repeated 24-hour urine collection is considered to be the gold standard for assessing salt intake. This is often impractical in large-population studies, especially in low–middle-income countries. Equations to estimate ...
A proposed cutoff point of waist-to-height ratio for metabolic risk in African township adolescents
(Elsevier, 2013)
Objective: A waist:height ratio (WHtR) higher than 0.5 has been proposed as a cutoff point for
abdominal obesity in both sexes and at all ages. It is unknown if this cutoff point is appropriate for
previously undernourished ...
Exploring the link between cardiovascular reactivity and end–organ damage in African and Caucasian men: the SABPA study
(Oxford University Press, 2013)
BACKGROUND Heart failure in the African population is reaching alarming levels. Increased afterload as a result of increased vasoconstriction during stress may lead to impaired ventricular function and stroke volume (SV) ...
Extracellular matrix biomarker, Fibulin–1 and Its association with Soluble uPAR in a Bi-ethnic South African population: the SAfrEIC study
(Elsevier, 2015)
Background
Fibulin-1 and soluble urokinase-type plasminogen activator receptor (suPAR) emerged as mediators in the development of sclerotic disease. SuPAR along with C-reactive protein (CRP) and albumin delineate ...
Ethnic differences regarding arterial stiffness of 6‐8‐year-old black and white boys
(Wolters Kluwer, 2017)
Objectives: Vascular deterioration is suggested to occur earlier in black than white populations, thereby increasing their risk for developing hypertension. To establish whether this is the case, we compared different ...
Prevalence of hypertension in older people in Africa: a systematic review and meta-analysis
(Wolters Kluwer, 2017)
Objective: The prevalence of hypertension in older people living on the African continent has not been comprehensively assessed. We aimed to provide accurate estimates of hypertension prevalence and variations by major ...
Leptin links with plasminogen activator inhibitor-1 in human obesity: the SABPA study
(Nature Publishing Group, 2015)
The relationship between obesity and the development of cardiovascular disease is well established. However, the underlying mechanisms contributing to vascular disease and increased cardiovascular risk in the obese remain ...
Soluble urokinase plasminogen activator receptor and hypertension among black South Africans after 5 years
(Nature Publishing Group, 2015)
Soluble urokinase plasminogen activator receptor (suPAR) is a biomarker that links inflammation with cardiovascular risk. "However, studies linking suPAR and hypertension are scant. First, we determined whether baseline ...
Leptin and its relation to autonomic activity, endothelial cell activation and blood pressure in a young black and white population: the African-PREDICT study
(Thieme, 2018)
An increasing prevalence of obesity-related hypertension is observed in the youth and may have severe consequences for future cardiovascular disease development. Previous studies portrayed leptin as a potential factor ...