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Social isolation rearing induces mitochondrial, immunological, neurochemical and behavioural deficits in rats, and is reversed by clozapine or N-acetyl cysteine
(Elsevier, 2013)
Apart from altered dopamine (DA) function, schizophrenia displays mitochondrial and immune-inflammatory
abnormalities, evidenced by oxidative stress, altered kynure nine metaboli sm and cytokine
release . N-acetyl cysteine ...
N-acetyl cysteine reverses social isolation rearing induced changes in cortico-striatal monoamines in rats
(Springer, 2013)
Schizophrenia is causally associated with early-life
environmental stress, implicating oxidative stress in its pathophysiology.
N-acetyl cysteine (NAC), a glutathione precursor
and antioxidant, is emerging as a useful ...