Now showing items 1-2 of 2
Synthesis and in vitro transdermal penetration of methoxypoly(ethylene glycol) carbonate derivatives of stavudine (3TC)
(Bentham Science, 2009)
The objective of this study was to synthesize derivatives of the anti-HIV drug stavudine (d4T) with more favourable physicochemical properties for transdermal delivery in an effort to increase transdermal penetration of ...
Synthesis of methodxypoly (ethylene glycol) carbonate prodrugs of zidovudine and penetration through human skin in vitro
The aim of this study was to synthesise a series of novel methoxypoly(ethylene glycol) carbonate prodrugs of the antiretroviral drug zidovudine (azidothymidine, AZT) in an attempt to enhance the physicochemical properties ...