Search
Now showing items 1-10 of 12
Testosterone and acute stress are associated with fibrinogen and Von Willebrand factor in African men: the SABPA study
(Elsevier, 2013)
Background: Low testosterone, acute and chronic stress and hypercoagulation are all associated with hypertension
and hypertension-related diseases. The interaction between these factors and future risk for coronary ...
Cornell product relates to albuminuria in hypertensive black adults independently of blood pressure: the SABPA study
(Elsevier, 2015)
Evidence of the relationship between left ventricular hypertrophy and urinary albumin excretion is contradictory and limited in black adults in whom hypertensive heart disease is common. We aimed to investigate the ...
The cardiotonic steroid marinobufagenin is a predictor of increased left ventricular mass in obesity: the African-PREDICT study
(MDPI, 2020)
The endogenous Na+/K+-ATPase inhibitor, marinobufagenin (MBG), strongly associates with salt intake and a greater left ventricular mass index (LVMi) in humans and was shown to promote cardiac fibrosis and hypertrophy in ...
The African prospective study on the early detection and identification of cardiovascular disease and hypertension (African-PREDICT): design, recruitment and initial examination
(Sage, 2019)
Background: Globally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an
increase. Although this might be attributed to poor healthcare and ineffective antihypertensive ...
The Exercise, Arterial Modulation and Nutrition in Youth South Africa Study (ExAMIN Youth SA)
(Frontiers Media, 2020)
Background: The impact of a sedentary and unhealthy lifestyle on cardiovascular
health is well-documented, however the current obesity and hypertension trends among
children is concerning. The ExAMIN Youth SA study aims ...
Sex hormones associated with subclinical kidney damage and atherosclerosis in South African men: the SABPA study
(Kluwer, 2012)
Background: Hypertension and increased blood glucose are associated with subclinical kidney damage, atherosclerosis and with low testosterone values. Low testosterone in men is often accompanied by increased levels of ...
Large artery stiffness is associated with salt intake in young healthy black but not white adults: the African-PREDICT study + Correction to article
(Springer, 2018)
Purpose
There is global consensus on the benefits of reducing excessive salt intake. Indeed, lower salt intake associates with reduced arterial stiffness, a well-established predictor of cardiovascular risk, in older ...
Marinobufagenin and left ventricular mass in young adults: the African-PREDICT study
(Sage, 2018)
Background
The endogenous steroidal inhibitor of sodium–potassium-dependent adenosine triphosphate and natriuretic hormone, marinobufagenin, plays a physiological role in ionic homeostasis. Animal models suggest that ...
Iron loading, alcohol and mortality: a prospective study
(Elsevier, 2019)
Background & aims
The relationship between total body iron and cardiovascular disease remains controversial and information absent in black sub-Saharan Africans in whom alcohol consumption tends to be high. The level of ...
The oxidative stress profile and its relation to vascular function in a bi-ethnic cohort: the SABPA study
(Karger, 2019)
Oxidative stress and inflammation
has been implicated in arterial stiffness, and hypertension development. Oxidative stress may interfere with normal vascular function by inactivation of NO and/or the production of ...