Now showing items 1-5 of 5
Cortico-striatal oxidative status, dopamine turnover and relation with stereotypy in the deer mouse
The deer mouse presents with spontaneous stereotypic movements that resemble the repetitive behaviours of obsessive–compulsive disorder (OCD), and demonstrates a selective response to serotonin reuptake inhibitors. OCD has ...
Role of monoamine oxidase, nitric oxide synthase and regional brain monoamines in the antidepressant-like effects of methylene blue and selected structural analogues
Dual action antidepressants have important therapeutic implications. Methylene blue (MB), a charged compound structurally related to tricyclic antidepressants, acts on both monoamine oxidase (MAO) and the nitric oxide ...
Symmetry symptoms in obsessive-compulsive disorder: clinical and genetic correlates
(Associação Brasileira de Psiquiatria (ABP), 2016)
Objective: In obsessive-compulsive disorder (OCD), symmetry-related symptoms may be important. Although clinical correlates of symmetry-related symptoms have been identified in OCD, few data exist on genetic associations. ...
The nature of relapse in schizophrenia
(BioMed Central, 2013)
Background: Multiple relapses characterise the course of illness in most patients with schizophrenia, yet the nature of these episodes has not been extensively researched and clinicians may not always be aware of important ...
Social isolation rearing induces mitochondrial, immunological, neurochemical and behavioural deficits in rats, and is reversed by clozapine or N-acetyl cysteine
Apart from altered dopamine (DA) function, schizophrenia displays mitochondrial and immune-inflammatory abnormalities, evidenced by oxidative stress, altered kynure nine metaboli sm and cytokine release . N-acetyl cysteine ...