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Animal models of major depressive disorder and the implications for drug discovery and development
(Taylor & Francis, 2019)
Introduction: Depression is a highly debilitating psychiatric disorder that affects the global population and causes severe disabilities and suicide. Depression pathogenesis remains poorly understood, and the disorder is ...
Abnormal repetitive behaviors in zebrafish and their relevance to human brain disorders
(Elsevier, 2019)
Abnormal repetitive behaviors (ARBs) are a prominent symptom of numerous human brain disorders and are commonly seen in rodent models as well. While rodent studies of ARBs continue to dominate the field, mounting evidence ...
Cross-species analyses of intra-species behavioral differences in mammals and fish
(Elsevier, 2020)
Multiple species display robust behavioral variance among individuals due to different genetic, genomic, epigenetic, neuroplasticity and environmental factors. Behavioral individuality has been extensively studied in various ...