Browsing Faculty of Health Sciences by Subject "Major depressive disorder"
Now showing items 1-4 of 4
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Animal models of major depressive disorder and the implications for drug discovery and development
(Taylor & Francis, 2019)Introduction: Depression is a highly debilitating psychiatric disorder that affects the global population and causes severe disabilities and suicide. Depression pathogenesis remains poorly understood, and the disorder is ... -
The impact of HIV/AIDS on compliance with antidepressant treatment in major depressive disorder: a prospective study in a South African private healthcare cohort
(BioMed Central, 2015)Background: MDD and HIV/AIDS have a high prevalence worldwide with severe consequences for patients. In both conditions, compliance with treatment is key to successfully treat these disorders. In the current study, ... -
Probiotic treatment protects against the pro-depressant-like effect of high-fat diet in Flinders Sensitive Line rats
(Elsevier, 2017)Major depressive disorder (MDD) is highly associated with dysmetabolic conditions, such as obesity and diabetes mellitus type 2, and the gut microbiota may interact with both disease entities. We have previously shown that ... -
Prospective analysis of the medicine possession ratio of antidepressants in the private health sector of South Africa, 2006-2011
(Health & Medical Publishing Group, 2015)Background: Major depressive disorder (MDD) is a disabling mental illness with high morbidity and mortality rates. Inadequate treatment efficacy, unfavourable side-effect profiles and consequent shortfalls in compliance ...