Now showing items 1-14 of 14

    • Are behavioural risk factors to be blamed for the conversion from optimal blood pressure to hypertensive status in black South Africans? A 5-year prospective study 

      Schutte, Rudolph; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Fourie, Carla M.T.; Schutte, Rudolph; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Fourie, Carla M.T. (Oxford University Press, 2012)
      Background Longitudinal cohort studies in sub-Saharan Africa are urgently needed to understand cardiovascular disease development. We, therefore, explored health behaviours and conventional risk factors of African individuals ...
    • The association of 25(OH)D with blood pressure, pulse pressure and carotid–radial pulse wave velocity in African women 

      Kruger, Iolanthé M.; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Schutte, Rudolph; Malan, Leoné; Malan, Nicolaas T.; Fourie, Carla M.T.; Kruger, Annamarie (Public Library of Science, 2013)
      High susceptibility of the African population to develop cardiovascular disease obliges us to investigate possible contributing risk factors. Our aim was to determine whether low 25(OH)D status is associated with increased ...
    • Blood glutathione and subclinical atherosclerosis in African men: the SABPA study 

      Schutte, Rudolph; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Malan, Nicolaas T.; Szabolcs, Péter; Fourie, Carla M.T.; Van der Westhuizen, Francois H.; Louw, Roan; Botha, Cindy A.; Malan, Leoné; Louw, Roan; Botha, Cindy A.; Malan, Leoné; Schutte, Rudolph; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Malan, Nicolaas T.; Szabolcs, Péter; Fourie, Carla M.T.; Van der Westhuizen, Francois H. (Oxford Univ Press, 2009)
      Background: Sub-Saharan Africans face an increasing burden of hypertension and related cardiac and cerebrovascular morbidity and mortality, making the identification of factors leading to early vascular abnormalities ...
    • Classifying Africans with the Metabolic Syndrome 

      Schutte, Aletta E; Olckers, Antonel; Huisman, Hugo W; Van Rooyen, Johannes; Malan, Leone; Malan, Nicolaas T; Schutte, Rudolph; Schutte, Aletta E.; Olckers, Antonel; Huisman, Hugo W.; Van Rooyen, Johannes; Malan, Leoné; Malan, Nicolaas T.; Schutte, Rudolph (Thieme, 2009)
      This study was aimed to compare prevalences of the metabolic syndrome in Africans using five definitions as proposed by the World Health Organization (WHO), the European Group for the Study of Insulin Resistance (EGIR), ...
    • Ethnic and gender differences regarding the insulin-blood pressure relationship 

      Schutte, Aletta E; Huisman, Hugo W; Palmer, Iolanthe Marike; Schutte, Aletta E; Huisman, Hugo W.; Palmer, Iolanthe Marike (Elsevier, 2009)
      Ageing is associated with increased insulin and C-peptide levels. Due to a lack of data, our first aim was to establish whether this also holds true for Africans from South Africa. Our second aim was to determine whether ...
    • Exploring the link between cardiovascular reactivity and end–organ damage in African and Caucasian men: the SABPA study 

      Huisman, Hugo W.; Schutte, Aletta E.; Schutte, Rudolph; Van Rooyen, Johannes M.; Fourie, Carla M. T. (Oxford University Press, 2013)
      BACKGROUND Heart failure in the African population is reaching alarming levels. Increased afterload as a result of increased vasoconstriction during stress may lead to impaired ventricular function and stroke volume (SV) ...
    • Facilitated defensive coping, silent ischaemia and ECG left-ventricular hypertrophy: the SABPA study 

      Malan, Leoné; Huisman, Hugo W.; Van Rooyen, Johannes M.; Schutte, Rudolph; Schutte, Aletta E.; Fourie, Carla M.T.; Malan, Nico T.; De Geus, Eco J.C.N.; Malan, Leoné; Huisman, Hugo W.; Van Rooyen, Johannes M.; Schutte, Rudolph; Schutte, Aletta E.; Fourie, Carla M.T.; Malan, Nico T.; De Geus, Eco J.C.N. (Kluwer, 2012)
      Background: Defensive active coping responses (being-in-control, acceptance of the stressor as reality) have been associated with vascular hyper-responsiveness in urban Africans. However, the association between active ...
    • Hyperuricaemia is an independent factor for the metabolic syndrome in a sub-Saharan African population: A factor analysis 

      Malan, Nicolaas T.; Malan, Leoné; Huisman, Hugo W.; Schutte, Aletta E.; Reimann, Manja; Malan, Nicolaas T.; Malan, Leoné; Huisman, Hugo W.; Schutte, Aletta E.; Reimann, Manja (Elsevier Science Limited, 2008)
    • L-Carnitine and long-chain acylcarnitines are positively correlated with ambulatory blood pressure in humans: the SABPA study 

      Mels, Catharina M. C.; Schutte, Aletta E.; Erasmus, Elardus; Huisman, Hugo W.; Schutte, Rudolph; Fourie, Carla M.T.; Kruger, Ruan; Van Rooyen, Johannes M.; Smith, Wayne; Malan, Nicolaas T.; Malan, Leoné (Springer, 2013)
      The prevalence of hypertension in sub-Saharan Africa is increasing rapidly, and treatment remains challenging. Although the use of l-carnitine in treatment has received much attention, studies reporting on physiological ...
    • Low testosterone and hyperkinetic blood pressure responses in a cohort of South African men: the SABPA study 

      Malan, Nicolaas T.; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Schutte, Rudolph; Mels, Catharina M.; Steyn, Hendrik S.; Smith, Wayne; Fourie, Carla M.; Glyn, Matthew; Malan, Leoné (Taylor & Francis, 2013)
      Hypertension (HT) and the metabolic syndrome are major problems in Africa. The role of sex hormones in the cardiovascular profile of black Africans in South Africa has not been studied. Our objective was to study the ...
    • NT–proBNP, C–reactive protein and soluble uPAR in a Bi–ethnic male population: the SAfrEIC study 

      Kruger, Ruan; Schutte, Rudolph; Huisman, Hugo W.; Olsen, Michael H.; Schutte, Aletta E. (Public Library of Science, 2013)
      Objective and design: This cross-sectional study aimed to investigate associations between a marker of cardiac strain, the N-terminal prohormone B-type natriuretic peptide (NT-proBNP), and inflammation as reflected by ...
    • Sex hormones associated with subclinical kidney damage and atherosclerosis in South African men: the SABPA study 

      Malan, Nico T.; Hamer, Mark; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Mels, Catharina M.; Smith, Wayne; Fourie, Carla M.T.; Schutte, Rudolph; Kruger, Ruan; Malan, Leoné; Malan, Nico T.; Hamer, Mark; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Mels, Catharina M.; Smith, Wayne; Fourie, Carla M.T.; Schutte, Rudolph; Kruger, Ruan; Malan, Leoné (Kluwer, 2012)
      Background: Hypertension and increased blood glucose are associated with subclinical kidney damage, atherosclerosis and with low testosterone values. Low testosterone in men is often accompanied by increased levels of ...
    • A significant decline in IGF-I may predispose young Africans to subsequent cardiometabolic vulnerability 

      Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Malan, Leoné; Malan, Nicolaas T.; Fourie, Catharina M.T.; Louw, Roan; Van der Westhuizen, Francois H.; Schutte, Rudolph; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Malan, Leoné; Malan, Nicolaas T.; Fourie, Catharina M.T.; Louw, Roan; Van der Westhuizen, Francois H.; Schutte, Rudolph (Oxford Univ Press, 2010)
      Objectives: Low serum IGF-I is an independent risk factor for diabetes and cardiovascular disease. These noncommunicable diseases are extremely common in urban black South Africans, but their IGF-I concentration is unknown. ...
    • Testosterone and acute stress are associated with fibrinogen and von Willebrand factor in African men: the SABPA study 

      Malan, Nicolaas T.; Schutte, Alta E.; Huisman, Hugo W.; Schutte, Rudolph; Smith, Wayne; Mels, Carina M.; Kruger, Ruan; Meiring, Muriel; Van Rooyen, Johannes M.; Malan, Leoné (ELSEVIER, 2013)
      Background: Low testosterone, acute and chronic stress and hypercoagulation are all associated with hypertension and hypertension-related diseases. The interaction between these factors and future risk for coronary ...