Browsing Faculty of Health Sciences by Subject "Efflux"
Now showing items 1-4 of 4
-
Absorptive and secretory transport of selected artemisinin derivatives across Caco-2 cell monolayers
(Bentham Science, 2018)Background: Malaria continues to be a major health concern and affects more than 200 million people a year. Drugs currently used for treatment of malaria are increasingly rendered ineffectual by the ongoing emergence of ... -
Herb-drug pharmacokinetic interactions: transport and metabolism of indinavir in the presence of selected herbal products
(MDPI, 2015)Patients receiving anti-retroviral drug treatment are sometimes simultaneously taking herbal remedies, which may result in pharmacokinetic herb-drug interactions. This study aimed to determine if pharmacokinetic interactions ... -
Impact of traditional African medicine on drug metabolism and transport
(Taylor & Francis, 2014)Introduction: Africa is a continent of rich plant biodiversity with many indigenous plants having a long history of being used for medicinal purposes. A considerable number of patients consult traditional healers in ... -
Modulation of drug efflux by aloe materials: an in vitro investigation across rat intestinal tissue
(Medknow, 2013)Background: Clinically, significant herb-drug interactions have been previously documented and can be pharmacodynamic and/or pharmacokinetic in nature. Pharmacokinetic interactions have been attributed to induction or ...