Browsing Faculty of Health Sciences by Subject "TET1"

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Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene

Wei, Ya Bin; Wegener, Gregers; Melas, Philippe A.; Mathé, Aleksander A.; Lavebratt, Catharina (Oxford Univ Press, 2015)

Background: Epigenetic drugs like sodium butyrate (NaB) show antidepressant-like effects in preclinical studies, but the exact molecular mechanisms of the antidepressant effects remain unknown. While research using NaB has ...