Browsing Faculty of Health Sciences by Subject "Review"

Now showing items 1-2 of 2

A critical inquiry into marble-burying as a preclinical screening paradigm of relevance for anxiety and obsessive-compulsive disorder: mapping the way forward

De Brouwer, Geoffrey; Fick, Arina; Harvey, Brian Herbert; Wolmarans, De Wet (Springer, 2019)

Rodent marble-burying behavior in the marble-burying test (MBT) is employed as a model or measure to study anxiety- and compulsive-like behaviors or anxiolytic and anticompulsive drug action. However, the test responds ...
A psycho-behavioral perspective on modelling obsessive-compulsive disorder (OCD) in animals: the role of context

Wolmarans, De Wet; Stein, Dan J.; Harvey, Brian Herbert (Bentham Science, 2017)

Obsessive-compulsive disorder is a heterogeneous and debilitating condition, characterized by intrusive thoughts and compulsive repetition. Animal models of OCD are important tools that have the potential to contribute ...