Browsing Faculty of Health Sciences by Subject "Fibrinolysis"

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Depression symptoms facilitated fibrinolytic dysregulation and future coronary artery disease risk in a black male cohort: the sympathetic activity and ambulatory blood pressure in Africans study

Malan, Leoné; Mashele, Nyiko; Malan, Nicolaas T.; Harvey, Brian Herbert; Potgieter, Johan C.; Van Rooyen, Johannes M. (Wolters Kluwer, 2017)

Background: Hypercoagulation is associated with coronary artery disease (CAD). Whether depression symptoms dysregulate inflammatory and hemostatic markers in an African cohort is not known; therefore, we assessed the ...
Fibrinogen and fibrin: an illustrated review

Pieters, Marlene; Wolberg, Alisa S. (Wiley, 2019)

Since its discovery over 350 years ago, studies of fibrinogen have revealed remarkable characteristics. Its complex structure as a large (340 kDa) hexameric homodimer supports complex roles in hemostasis and homeostasis. ...
Leukocyte telomere length and hemostatic factors in a South African cohort: the SABPA study

Von Känel, R.; Malan, N.T.; Hamer, M.; Van der Westhuizen, F.H.; Malan, L. (Wiley, 2014)

Background Incident atherothrombotic disease is predicted by leukocyte telomere length, a marker of biological age, and hemostatic factor levels, indicating a hypercoagulable state. We hypothesized that shorter telomeres ...