Browsing Faculty of Health Sciences by Subject "Dual action"

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Role of monoamine oxidase, nitric oxide synthase and regional brain monoamines in the antidepressant-like effects of methylene blue and selected structural analogues

Harvey, Brian Herbert; Duvenhage, Ingrid; Viljoen, Francois; Scheepers, Nellie; Brink, Christiaan B.; Petzer, Jacobus P.; Malan, Sarel F. (Elsevier, 2010)

Dual action antidepressants have important therapeutic implications. Methylene blue (MB), a charged compound structurally related to tricyclic antidepressants, acts on both monoamine oxidase (MAO) and the nitric oxide ...