Browsing Faculty of Health Sciences by Subject "Cell culture"

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Models used to screen for the treatment of multidrug resistant cancer facilitated by transporter-based efflux

Willers, Clarissa; Svitina, Hanna; Rossouw, Michael J.; Swanepoel, Roan A.; Hamman, Josias H.; Gouws, Chrisna (Springer, 2019)

Purpose Efflux transporters of the adenosine triphosphate-binding cassette (ABC)-superfamily play an important role in the development of multidrug resistance (multidrug resistant; MDR) in cancer. The overexpression of ...