Browsing Faculty of Health Sciences by Author "Wegener, G."
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3D analysis of synaptic vesicle density and distribution after acute foot‐shock stress by using serial section transmission electron microscopy
Khanmohammadi, M.; Wegener, G.; Darkner, S.; Nava, N.; Nyengaard, J.R. (Wiley, 2017)Behavioural stress has shown to strongly affect neurotransmission within the neocortex. In this study, we analysed the effect of an acute stress model on density and distribution of neurotransmitter‐containing vesicles ... -
Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression
Melas, P.A.; Wegener, G.; Lennartsson, A.; Vakifahmetoglu-Norberg, H.; Wei, Y. (Springer Nature, 2013)Neuropeptide Y (NPY) has been implicated in depression, emotional processing and stress response. Part of this evidence originates from human single-nucleotide polymorphism (SNP) studies. In the present study, we report ... -
Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression
Wei, Y.B.; Wegener, G.; Liu, J.J.; Villaescusa, J.C.; Åberg, E. (Springer Nature, 2016)Elevation of the proinflammatory cytokine IL-6 has been implicated in depression; however, the mechanisms remain elusive. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit gene expression post-transcriptionally. ...