Browsing Faculty of Health Sciences by Author "Grobler, Paul"
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Inhibition of monoamine oxidase by selected phenylalkylcaffeine analogues
Petzer, Anél; Grobler, Paul; Bergh, Jacobus J.; Petzer, Jacobus P. (Wiley, 2014)Objectives Caffeine represents a useful scaffold for the design of monoamine oxidase (MAO) type B inhibitors. Specifically, substitution on the C8 position yields structures which are high-potency MAO-B inhibitors. To ...