Now showing items 1-3 of 3

    • Leveraging the urban-rural divide for epigenetic research 

      Cronjé, Héléne T.; Nienaber-Rousseau, Cornelie; Pieters, Marlien; Elliott, Hannah R. (Future Medicine, 2020)
      Urbanization coincides with a complex change in environmental exposure and a rapid increase in noncommunicable diseases (NCDs). Epigenetics, including DNA methylation (DNAm), is thought to mediate part of the association ...
    • Methylation vs. protein inflammatory biomarkers and their associations with cardiovascular function 

      Cronjé, Héléne Toinét; Nienaber-Rousseau, Cornelie; Schutte, Aletta E.; Pieters, Marlien; Elliott, Hannah R. (Frontiers Media, 2020)
      DNA methylation data can be used to estimate proportions of leukocyte subsets retrospectively, when directly measured cell counts are unavailable. The methylation-derived neutrophil-to-lymphocyte and lymphocyte-to-monocyte ...
    • Replication and expansion of epigenomewide association literature in a black South African population 

      Cronjé, H. Toinét; Nienaber-Rousseau, Cornelie; Pieters, Marlien; Elliott, Hannah R. (BMC, 2020)
      DNA methylation is associated with non-communicable diseases (NCDs) and related traits. Methylation data on continental African ancestries are currently scarce, even though there are known genetic and epigenetic differences ...