Browsing Faculty of Health Sciences by Author "Chen, Jiang-Fan"
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Dual-target-directed drugs that block monoamine oxidase B and adenosine A2A receptors for Parkinson’s disease
Petzer, Jacobus P.; Castagnoli, Neal; Schwarzschild, Michael A.; Chen, Jiang-Fan; Van der Schyf, Cornelis J. (Springer, 2009)Inadequacies of the current pharmacotherapies to treat Parkinson’s disease (PD) have prompted efforts to identify novel drug targets. The adenosine A2A receptor is one such target. Antagonists of this receptor (A2A ...