Browsing Faculty of Health Sciences by Author "Baumgartner, Jeannine"
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Adjusting haemoglobin values for altitude maximizes combined sensitivity and specificity to detect iron deficiency among women of reproductive age in Johannesburg, South Africa
Silubonde, Takana Mary; Baumgartner, Jeannine; Malan, Linda; Smuts, Cornelius Matheus; Ware, Lisa Jayne (MDPI, 2020)In South Africa, haemoglobin (Hb) is measured to screen for iron deficiency (ID). However, low levels of Hb are only a late stage indicator of ID. Furthermore, Hb values are generally not adjusted for altitude even though ... -
Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth, and psychomotor development in 6‐month‐old South African infants
Siziba, Linda P.; Baumgartner, Jeannine; Ricci, Cristian; Jacobs, Adriaan; Rothman, Marinel; Matsungo, Tonderayi M.; Faber, Mieke; Smuts, Cornelius M. (Wiley, 2019)The objective of this study was to assess plasma fatty acid (FA) patterns of 6‐month‐old South African infants and to determine their association with feeding practices, growth, and psychomotor development. Plasma total ... -
Breast milk and erythrocyte fatty acid composition of lactating women residing in a peri‑urban South African township
Siziba, Linda P.; Chimhashua, Tsitsi; Siro, Sicelosethu S.; Jacobs, Adriaan; Malan, Linda; Smuts, Cornelius M.; Baumgartner, Jeannine (Elsevier, 2020)Data on breast milk fatty acid (FA) composition in South African lactating women in relation to their FA status, as well as on potential compositional changes within feed, are limited. The aim of this study was to assess ... -
Chemical composition, but not specific surface area, affects calcium retention of nanostructured calcium compounds in growing rats
Posavec, Lidija; Baumgartner, Jeannine; Buntting, Hylton; Grobler, Anne F.; Hilty, Florentine M. (Oxford Univ Press, 2017)Background: Low dietary calcium intake and bioavailability may adversely affect bone health. Reducing the size of calcium compounds increases their specific surface area (SSA, expressed as m2/g) and may increase calcium ... -
Combined deficiency of iron and (n-3) fatty acids in male rats disrupts brain monoamine metabolism and produces greater memory deficits than iron deficiency or (n-3) fatty acid deficiency alone1-3
Baumgartner, Jeannine; Smuts, Cornelius M.; Malan, Linda; Arnold, Myrtha; Yee, Benjamin K. (American Society of Nutrition (ASN), 2012)Deficiencies of iron (Fe) (ID) and (n-3) fatty acids (FA) [(n-3)FAD] may impair brain development and function through shared mechanisms. However, little is known about the potential interactions between these 2 common ... -
Determining sample size adequacy for animal model studies in nutrition research: limits and ethical challenges of ordinary power calculation procedures
Ricci, Cristian; Baumgartner, Jeannine; Malan, Linda; Smuts, Cornelius M. (Taylor & Francis, 2020)Animal models are widely used in the field of nutrition research. Scientifically and ethically sound experiments need an adequate number of experimental units. The use of 5-10 units is common, but such sample sizes can be ... -
Different dietary fatty acids are associated with blood lipids in healthy South African men and women: the PURE study
Richter, Marilize; Baumgartner, Jeannine; Wentzel-Viljoen, Edelweiss; Smuts, Cornelius M. (Elsevier, 2014)Background: Preliminary data from the baseline Prospective Urban Rural Epidemiology (PURE) study in South Africa indicated a higher prevalence of dyslipidemia than previous South African studies. The intake of specific ... -
Effects of a multi-micronutrient-fortified beverage, with and without sugar, on growth and cognition in South African schoolchildren: a randomised, double-blind, controlled intervention
Taljaard, Christine; Covic, Namukolo M.; Van Graan, Averalda E.; Kruger, Herculina S.; Smuts, Cornelius M.; Baumgartner, Jeannine; Wright, Hattie H.; Jerling, Johann C. (Cambridge University Press, 2013)Little is known about the effects of combined micronutrient and sugar consumption on growth and cognition. In the present study, we investigated the effects of micronutrients and sugar, alone and in combination, in a ... -
Effects of iron and n-3 fatty acid supplementation, alone and in combination, on cognition in school children: a randomized, double-blind, placebo-controlled intervention in South Africa
Baumgartner, Jeannine; Smuts, Cornelius Mattheus; Malan, Linda; Kvalsvig, Jane; Van Stuijvenberg, M.; Hurrell, Richard; Zimmermann, Michael B. (American Society for Nutrition (ASN), 2012)Background: Little is known about the combined effects of iron and n−3 (omega-3) fatty acid (FA) supplementation on cognitive performance. The provision of either DHA/EPA or iron alone in rats with combined iron and n−3 ... -
Effects of wheat-flour biscuits fortified with iron and EDTA, alone and in combination, on blood lead concentration, iron status, and cognition in children: a double-blind randomized controlled trial
Bouhouch, Raschida R.; Baumgartner, Jeannine; El-Fadeli, Sana; Andersson, Maria; Aboussad, Abdelmounaim (ASN, 2016)Background: Lead is a common neurotoxicant and its absorption may be increased in iron deficiency (ID). Thus, iron fortification to prevent ID in populations is a promising lead mitigation strategy. Two common fortificants ... -
Efficacy of novel small-quantity lipid-based nutrient supplements in improving long-chain polyunsaturated fatty acid status of South African infants: a randomised controlled trial
Siziba, Linda P.; Baumgartner, Jeannine; Rothman, Marinel; Matsungo, Tonderayi M.; Smuts, Cornelius M. (Springer, 2020)Background/objectives The objective of this study was to investigate the efficacy of small-quantity lipid-based nutrient supplements (SQ-LNS) containing essential fatty acids (EFAs) with or without long-chain polyunsaturated ... -
How will South Africa’s mandatory salt reduction policy affect its salt iodisation programme? A cross-sectional analysis from the WHO-SAGE Wave 2 Salt & Tobacco study
Charlton, Karen; Ware, Lisa Jane; Baumgartner, Jeannine; Cockeran, Marike; Schutte, Aletta E. (BMJ Publishing Group, 2018)Objective The WHO’s global targets for non-communicable disease reduction recommend consumption of<5 g salt/day. In 2016, South Africa was the first country to legislate maximum salt levels in processed foods. South Africa’s ... -
In male rats with concurrent iron and (n-3) fatty acid deficiency, provision of either iron or (n-3) fatty acids alone alters monoamine metabolism and exacerbates the cognitive deficits associated with combined deficiency 1-3
Baumgartner, Jeannine; Smuts, Cornelius M.; Malan, Linda; Arnold, Myrtha; Yee, Benjamin K.; Yee, Benjamin K. (American Society of Nutrition (ASN), 2012)Concurrent deficiencies of iron (Fe) (ID) and (n-3) fatty acids [(n-3)FAD)] in rats can alter brain monoamine pathways and impair learning and memory. We examined whether repletion with Fe and DHA/EPA, alone and in ... -
Iodine status and associations with feeding practices and psychomotor milestone development in six-month-old South African infants
Osei, Jennifer; Baumgartner, Jeannine; Rothman, Marinel; Matsumgo, Tonderayi M.; Smuts, Cornelius M.; Covic, Namukolo (Wiley, 2017)Iodine is important for normal growth and psychomotor development. While infants below 6 months of age receive iodine from breast milk or fortified infant formula, the introduction of complementary foods poses a serious ... -
Iodine status assessment in South African adults according to spot urinary iodine concentrations, prediction equations, and measured 24-h iodine excretion
Charlton, Karen E.; Ware, Lisa J.; Baumgartner, Jeannine; Cockeran, Marike; Schutte, Aletta E. (MDPI, 2018)The iodine status of populations is conventionally assessed using spot urinary samples to obtain a median urinary iodine concentration (UIC) value, which is assessed against standard reference cut-offs. The assumption that ... -
Long-chain n-3 PUFA supplementation decreases physical activity during class time in iron-deficient South African school children
Smuts, Cornelius M.; Greeff, Jani; Kvalsvig, Jane; Zimmermann, Michael B.; Baumgartner, Jeannine (Georg Thieme Verlag, 2015)Both Fe deficiency and poor n-3 fatty acid status have been associated with behavioural changes in children. In the present study, we investigated the effects of Fe and DHA+EPA supplementation, alone or in combination, on ... -
Long-chain polyunsaturated fatty acids are associated with blood pressure and hypertension over 10-years in black South African adults undergoing nutritional transition
Zec, Manja; Schutte, Aletta E.; Ricci, Cristian; Baumgartner, Jeannine; Kruger, Iolanthé M.; Smuts, Cornelius M. (MDPI, 2019)Nutritional transition in Africa is linked with increased blood pressure (BP). We examined 10-year fatty acid status and longitudinal associations between individual long-chain polyunsaturated fatty acids (PUFA), BP and ... -
Missing data imputation via the expectation-maximization algorithm can improve principal component analysis aimed at deriving biomarker profiles and dietary patterns
Malan, Linda; Smuts, Cornelius M.; Baumgartner, Jeannine; Ricci, Cristian (Elsevier, 2020)Principal component analysis (PCA) is a popular statistical tool. However, despite numerous advantages, the good practice of imputing missing data before PCA is not common. In the present work, we evaluated the hypothesis ... -
n-3 Long-chain PUFAs reduce respiratory morbidity caused by iron supplementation in iron-deficient South African schoolchildren: a randomized, double-blind, placebo-controlled intervention
Malan, Linda; Baumgartner, Jeannine; Calder, Philip; Zimmermann, Michael; Smuts, Cornelius Mattheus (American Society for Nutrition, 2015)ABSTRACT Background: Although iron supplementation in malaria–free areas "mostly reduces infectious morbidity, it can sometimes increase morbidity" from infections as a result of the dependence of pathogenic ... -
Nutrition during pregnancy and early development (NuPED) in urban South Africa: a study protocol for a prospective cohort
Symington, Elizabeth A.; Baumgartner, Jeannine; Malan, Linda; Zandberg, Lizelle; Ricci, Cristian; Smuts, Cornelius M. (BioMed Central, 2018)Background Adequate nutrition during pregnancy is important to ensure optimal birth outcomes, maternal health and offspring development. However, little is known about the dietary intake and nutritional status of pregnant ...