Browsing Faculty of Health Sciences by Author "20984634 - Du Plessis, Jesslee Melinda"
Now showing items 1-9 of 9
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Acute changes in haematocrit leading to polycythaemia in late-onset hypogonadism patients that receive testosterone replacement therapy: a South African study
Du Plessis, Jesslee; Bester, Hermanus Lambertus; Julyan, Marlene; Cockeran, Marike (Taylor & Francis, 2019)Background: According to the literature, parenteral testosterone replacement therapy (TRT)-induced polycythaemia is associated with cardiovascular events. No or minimal data exist for the prevalence of TRT-induced ... -
Assessment of post-operative pain medication adherence after day case orthopaedic surgery: a prospective, cross-sectional study
Booysen, Vanessa; Burger, Johanita R.; Du Plessis, Jesslee M.; Cockeran, Marike (Elsevier, 2020)Background and aim Patients struggle to adhere to prescribed pain medication after surgery because of, inter alia, side effects, sleep disturbances and pain severity. This study aimed to determine the influence of various ... -
Asthma control limitations in selected primary health care clinics
Du Plessis, Jesslee M.; Gerber, Jan J. (AOSIS, 2009)Primary health care services worldwide are currently experiencing many quality-related problems. Efforts to improve these services appear to be sporadic and unsatisfactory. Investigations have revealed (Sharma & Sharma ... -
Hypertriglyceridaemia and the risk of pancreatitis six months post lopinavir/ritonavir initiation
Greffrath, Wilhelm P.; Du Plessis, Jesslee M.; Viljoen, Michelle; Cockeran, Marike (AOSIS, 2018)Background: Hypertriglyceridaemia (HTG) is an important risk factor for pancreatitis and cardiovascular disease (CVD), depending on severity. Hypertriglyceridaemia is common in human immunodeficiency virus (HIV) infection ... -
Investigation of the coexistence of CKD and non-communicable chronic diseases in a PBM company in South Africa
Meuwesen, W.P.; Du Plessis, J.M.; Burger, J.R.; Lubbe, M.S.; Cockeran, M. (Taylor & Francis, 2016)Background: Chronic kidney disease (CKD) is a public health problem, with increasing global prevalence. Several factors could influence the prognosis of CKD, including comorbid chronic conditions. This study investigated ... -
Is guideline-driven prophylaxis for venous thromboembolism common practice in the South African private hospital setting?
Van der Merwe, Melissa; Julyan, Marlene; Du Plessis, Jesslee M. (AOSIS, 2020)Background: Prophylactic venous thromboembolism (VTE) strategies have the greatest impact on patient outcomes. Both global and local guidelines support VTE prophylaxis for hospitalised patients. However, studies have ... -
Managing asthma in primary care through imperative outcomes
Du Plessis, Jesslee M.; Gerber, Jan J.; Brand, Linda (Wiley, 2013)Rationale, aims and objectives To evaluate asthma management and control in primary care clinics so as to design improvements based on guideline-directed outcomes. Methods In this study, all medical records of asthma-diagnosed ... -
Prescribing patterns of non-steroidal anti-inflammatory drugs in chronic kidney disease patients in the South African private sector
Meuwesen, Willem P.; Du Plessis, Jesslee M.; Burger, Johanita R.; Lubbe, Martie S.; Cockeran, Marike (Springer, 2016)Background Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used pharmaceutical agents worldwide. NSAIDs are considered nephrotoxic and should therefore be used with caution or be avoided completely ... -
The use of cytokines as indicators for drug safety
Griessel, Helene; Pheiffer, Wihan; Du Plessis, Jesslee; Grobler, Anne Frederica; Zeevaart, Jan-Rijn (Elsevier, 2019)In developing new compounds, questions about safety and efficacy are raised. Conventional preclinical studies of new compounds focus on bio-distribution, toxicology, safety pharmacology, pharmacokinetics, efficacy etc., ...