Browsing Faculty of Health Sciences by Author "10062688 - Marais, Andries Francois"
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Direct compression of chitosan: process and formulation factors to improve powder flow and tablet performance
Buys, Gerhard M.; Du Plessis, Lissinda H.; Marais, Andries F.; Kotzé, Awie F.; Hamman, Josias H. (Bentham Science, 2013)Chitosan is a polymer derived from chitin that is widely available at relatively low cost, but due to compression challenges it has limited application for the production of direct compression tablets. The aim of this study ... -
Effect of moisture content, temperature and exposure time on the physical stability of chitosan powder and tablets
Viljoen, Joe M.; Steenekamp, Jan H.; Marais, Andries F.; Kotzé, Awie F. (Taylor & Francis, 2014)Context: Chitosan does not rank highly regarding its employment as tablet filler due to certain limitations. Undesirable properties that limit its utilization as excipient in solid dosage forms include its hydration ...