Browsing Faculty of Health Sciences by Author "10059059 - Tiedt, Louwrens Rasmus"
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Dissipative particle dynamics investigation of the transport of salicylic acid through a simulated in vitro skin permeation model
Otto, Daniel P.; Combrinck, Johann; Otto, Anja; Tiedt, Louwrens R.; De Villiers, Melgardt M. (MDPI, 2018)Permeation models are often used to determine diffusion properties of a drug through a membrane as it is released from a delivery system. In order to circumvent problematic in vivo studies, diffusion studies can be ... -
Influence of the composition of water/ethanol mixtures on the solubility and recrystallization of nevirapine
Stieger, Nicole; Liebenberg, Wilna; Tiedt, Louwrens R.; Wessels, Johanna C.; Caira, Mino R. (ACS, 2010)Anhydrous nevirapine was recrystallized from ethanol containing various amounts of water to determine its effects on the products obtained. The solubility of the anhydrous form was determined for each of the binary solvent ... -
The SeDeM expert diagram system: its performance and predictability in direct compressible formulations containing novel excipients and different types of active ingredients
Scholtz, Jacques C.; Steenekamp, Jan H.; Hamman, Josias H.; Tiedt, Louwrens R. (Elsevier, 2017)The SeDeM Expert Diagram System is a galenic pre-formulation system, which evaluates the suitability of excipients and active pharmaceutical ingredients (API's) for direct compression into tablets as well as predicting ...