Browsing Faculty of Health Sciences by Author "10057579 - Van Tonder, Elizabeth Cornelia"
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Physicochemical properties of amorphous roxithromycin prepared by quench cooling of the melt or desolvation of a chloroform solvate
Aucamp, Marique; Liebenberg, Wilna; Strydom, Schalk J.; Van Tonder, Elsa C.; De Villiers, Melgardt M. (Springer, 2012)Roxithromycin is a poorly soluble antibacterial drug. The aim of this study was to prepare and characterize an amorphous form of roxithromycin. The amorphous form was prepared by desolvation of its chloroform solvate, and ...