Browsing Faculty of Health Sciences by Issue Date
Now showing items 21-40 of 2404
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Medicinal chemistry of polycyclic cage compounds in drug discovery research
(Springer, 2008)Saturated polycyclic hydrocarbon structures such as the monocyclic octane, bicylic norbornane and tricyclic adamantane have attracted the attention of several research groups since the 1930s. In the 1950s the synthesis of ... -
Synthesis, complete 1H and 13C NMR assignment and crystal structure of novel epoxide derivatives of cytochalasin B
(University of Stellenbosch, 2008)Five novel epoxide derivatives of cytochalasin B were synthesized. Reaction of cytochalasin B with t-BHP and BuLi led to selective epoxidation of the C-21/22 double bond to give a single monoepoxide, while reaction with ... -
Dermal exposure sampling methods: an overview
(South African Society of Occupational Medicine, 2008) -
The protective effect of plasma antioxidants during ozone autohemotherapy
(Academic Journals, 2008)Ozone (O3) therapy forms part of a group of complementary and alternative medical therapies and is gaining more and more interest worldwide. There is, however, some concern regarding O3-toxicity and uncertainty about the ... -
Evaluation of the mental health continuum-short form (MHC-SF) in Setswana-speaking South Africans
(Wiley, 2008)A continuous assessment and a categorical diagnosis of the presence of mental health, described as flourishing, and the absence of mental health, characterized as languishing, is applied to a random sample of 1050 ... -
Deuterium isotope effects for the oxidation of 1-methyl-3phenyl-3pyrrolinyl analogues by monoamine oxidase B
(Elsevier, 2008)The parkinsonian inducing agent, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), is a cyclic tertiary allylamine exhibiting good monoamine oxidase B (MAO-B) substrate properties. MAO-B catalyzes the ring α-carbon ... -
Development and tracking of Body Mass Index from preschool age into adolescence in rural South African children: Ellisras longitudinal growth and health study.
(Centre for Health and Population Research, 2008) -
Knowledge of intrapartum practices to limit vertical transmission of HIV
(Elsevier Science Ltd, 2008) -
The qualitative research proposal
(Democratic Nursing Organisation of South Africa (DENOSA), 2008) -
Experiences of HIV/AIDS stigma of persons living with HIV/AIDS and nurses involved in their care from five african countries
(Department Health Studies, University of South Africa, 2008) -
Measuring the glycemic index of foods: interlaboratory study
(American Society for Nutrition, 2008) -
Dual inhibition of monoamine oxidase B and antagonism of the adenosine A2A receptor by (E,E)-8-(4phenylbytadien-1-yl) caffeine analogues
(Elsevier, 2008)The adenosine A2A receptor has emerged as an attractive target for the treatment of Parkinson’s disease (PD). Evidence suggests that antagonists of the A2A receptor (A2A antagonists) may be neuroprotective and may help to ... -
Fluorescent polycyclic ligands for nitric oxide synthase (NOS) inhibition
(Elsevier, 2008)In recent years polycyclic compounds have been shown to exhibit pharmacological profiles of importance in the symptomatic and proposed curative treatment of neurodegenerative diseases (e.g., Parkinson’s and Alzheimer’s ... -
Coping with urbanization: a cardiometabolic risk? The THUSA study
(Elsevier, 2008)An assessment of specific coping styles in rural-urban Africans is done to evaluate its contribution as cardiometabolic risk factor. In total, 608 apparently healthy Africans were included in a cross-sectional comparative ... -
Overfatness, stunting and physical inactivity are determinants of plasminogen activator
(Wolters Kluwer, 2008) -
Genetic polymorphisms of beta(2)- and beta(3)- adrenergic receptor genes associated with characteristics of the metabolic syndrome in black South African women
(Thieme, 2008)Background: Genetic variation in the β2 (ADRB2) and β3 (ADRB3) adrenergic receptor genes are associated with obesity and insulin resistance. To further elucidate the role of these genes in the pathophysiology of obesity ... -
Hyperuricaemia is an independent factor for the metabolic syndrome in a sub-Saharan African population: a factor analysis
(Elsevier, 2008)Objective To assess the risk factor pattern of the metabolic syndrome and its association with insulin resistance and hyperuricaemia in a sub-Saharan African population with different levels of urbanisation. Methods Four ...
