Browsing Faculty of Health Sciences by Title
Now showing items 41-60 of 2386
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Acceptability of chevon from kids, yearling goats and mature does of indigenous South African goats: a case study
(South African Society for Animal Science (SASAS), 2008) -
Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites
(Nature, 2018)The quinolone decoquinate is coadministered with feed for treatment of parasites which cause coccidiosis in poultry. However, from a drug-development perspective, the biological activity is often not adequately exploited ... -
Accumulation of TB-active compounds in murine organs relevant to infection by mycobacterium tuberculosis
(Frontiers Media, 2020)Tuberculosis (TB), the leading cause of death due to an infectious agent, requires prolonged and costly drug treatments. With the rise in incidence of MDR and XDR TB, newer more efficacious treatments which are better ... -
The accuracy in measurement of blood pressure (AIM‐BP) collaborative: background and rationale
(Wiley, 2019)Blood pressure (BP) measurement, a technique first described over a century ago, is an essential component of clinical care and critical for the detection and management of hypertension.1 Accordingly, the ramifications ... -
Accuracy of the prediction equation for the determination of maximum heart rate in adults with Down syndrome
(Wiley, 2017)Background The purpose of the study was to determine if the regression formula developed for the prediction of maximum heart rate (HR) is valid for adults with Down syndrome (DS). Methods Thirty‐six adults with DS ... -
Activities of 11-azaartemisinin and N-sulfonyl derivatives against asexual and transmissible malaria parasites
(Wiley, 2017)Dihydroartemisinin (DHA), either used in its own right or as the active drug generated in vivo from the other artemisinins in current clinical use—artemether and artesunate—induces quiescence in ring-stage parasites of ... -
Activities of 11-azaartemisinin and N-sulfonyl derivatives against Neospora caninum and comparative cytotoxicities
(Wiley, 2017)Neosporosis caused by the apicomplexan parasite Neospora caninum is an economically important disease that induces abortion in dairy and beef cattle. There are no vaccines or drugs available on the market for control or ... -
Activity preferences of 9- to 10-year-old girls and the relationship between object control skills and physical activity levels : the NW-Child Study
(Univ Stellenbosch, 2017)Early object control (OC) skills proficiency is reported to be related to long-term physical activity (PA). The percentage of participation in moderate- and high-intensity PAs and the relationship between PA levels and OC ... -
Acute changes in haematocrit leading to polycythaemia in late-onset hypogonadism patients that receive testosterone replacement therapy: a South African study
(Taylor & Francis, 2019)Background: According to the literature, parenteral testosterone replacement therapy (TRT)-induced polycythaemia is associated with cardiovascular events. No or minimal data exist for the prevalence of TRT-induced ... -
Added sugar intake in South Africa: findings from the Adult Prospective Urban and Rural Epidemiology cohort study1-4
(American Society for Nutrition (ASN), 2014)Background: Obesity and other noncommunicable disease (NCD) risk factors are increasing in low- and middle-income countries. There are few data on the association between increased added sugar intake and NCD risk in these ... -
Added sugar, macro- and micronutrient intakes and anthropometry of children in a developing world context
(Public Library of Science, 2015)Objective The objective of this study was to determine the relationship between added sugar and dietary "diversity, micronutrient intakes and anthropometric status in a nationally representative" "study of children, 1 8.9 ... -
Addressing low-literacy in the South African clothing retail environment
(SAAFECS, 2017)Low-literate consumers display distinctive behaviour in the marketplace, which entails concrete thinking (for example, the use of single pieces of information) and pictographic thinking (for example, the use of information ... -
Addressing non-communicable diseases in the Western Cape, South Africa
(PAGEPress, 2019)Background: Chronic non-communicable diseases (CNCDs) are increasing with grave consequences to countries’ development. The purpose of this study was three-fold: (1) to determine challenges PURE study participants faced ... -
The adenosine A2A antagonistic properties of selected C8-substituted xanthines
(Elsevier, 2013)The adenosine A2A receptor is considered to be an important target for the development of new therapies for Parkinson’s disease. Several antagonists of the A2A receptor have entered clinical trials for this purpose and ... -
The adenosine receptor affinities and monoamine oxidase B inhibitory properties of sulfanylphthalimide analogues
(Elsevier, 2015)Based on a report that sulfanylphthalimides are highly potent monoamine oxidase (MAO) B selective inhibitors, the present study examines the adenosine receptor affinities and MAO-B inhibitory properties of a series of 4- ... -
Adherence challenges encountered in an intervention programme to combat chronic non-communicable diseases in an urban black community, Cape Town
(AOSIS, 2017)Background: Chronic non-communicable diseases (CNCD) have become the greatest contributor to the mortality rate worldwide. Despite attempts by Governments and various non-governmental organisations to prevent and control ... -
Adipokines and cardiometabolic function: how are they interlinked?
(Elsevier, 2010)Objective Adipokines contribute directly to the coexistence of insulin resistance and endothelial dysfunction. Most studies focus on a single adipokine. We therefore investigated the independent relationships of leptin, ... -
Adiposity and physical activity are related to heart rate variability: the African-PREDICT study
(Wiley, 2020)Background Physical inactivity contributes significantly to the development of obesity‐related cardiovascular disease. Adiposity may lead to reduced heart rate variability (HRV), whereas increased physical activity (PA) ... -
Adjusting haemoglobin values for altitude maximizes combined sensitivity and specificity to detect iron deficiency among women of reproductive age in Johannesburg, South Africa
(MDPI, 2020)In South Africa, haemoglobin (Hb) is measured to screen for iron deficiency (ID). However, low levels of Hb are only a late stage indicator of ID. Furthermore, Hb values are generally not adjusted for altitude even though ...