Browsing Faculty of Health Sciences by Title
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Nonuniform internal structure of fibrin fibers: protein density and bond density strongly decrease with increasing diameter
(Hindawi, 2017)Themajor structural component of a blood clot is ameshwork of fibrin fibers. It has long been thought that the internal structure of fibrin fibers is homogeneous; that is, the protein density and the bond density between ... -
Notational singles match analysis of male badminton players who participated in the African Badminton Championships
(Taylor & Francis, 2017)Purposes of this study were firstly, to determine the notational singles match analysis results of male badminton players and secondly, to determine relationships between notational singles match analysis determined strokes ... -
A novel HPLC method developed and validated for the detection and quantification of atorvastatin, fluvastatin, pitavastatin and pravastatin during transdermal delivery studies
(Govi-Verlag, 2020)An HPLC method was developed and validated to quantify and identify several statins (atorvastatin, fluvastatin, pitavastatin and pravastatin) that were used during transdermal drug delivery. The method proved to be most ... -
Novel monoamine oxidase inhibitors based on the privileged 2-imidazoline molecular framework
(Elsevier, 2019)Series of structurally diverse 2-imidazoline derivatives have been synthesized by condensation of substituted aldehydes with ethylenediamine, Pd-catalyzed N-arylation of 2-imidazolines and by the formation of 1,2,4-oxadiazoles ... -
Novel monoamine oxidase inhibitors: a patent review (2012-2014)
(Taylor & Francis, 2015)Introduction: Monoamine oxidase (MAO) inhibitors, despite the initial pharmacological interest, are used in clinic for their antidepressant effect and in the management of Parkinson symptoms, due to the established ... -
Novel non-invasive protein and peptide drug delivery approaches
(Bentham Science, 2014)Protein and peptide based therapeutics are typically administered by injection due to their poor uptake when administered via enteral routes of drug administration. Unfortunately, chronic administration of these drugs ... -
A novel reversed-phase LC method for quantitative detection of azithromycin in bulk drug and tablet formulations in various aqueous media
(Avoxa, 2012)A novel reversed-phase HPLC method with UV-detection for separation, identification and quantification of azithromycin (AZH) was developed. The method was validated for the purpose of quantifying AZH in stability, ... -
A novel RP-HPLC method for the detection and quantification of clarithromycin or spiramycin in bulk drug samples and dosage forms
(Innovare Academic Sciences, 2016)Objective: This study was aimed at developing an HPLC method that would be suitable and sufficiently robust to analyze clarithromycin or spiramycin from bulk materials, amorphous solid dispersions as well as when included ... -
A novel RP-HPLC method for the detection and quantification of roxithromycin in topical delivery studies
(Govi-Verlag, 2015)A novel HPLC method with UV detection for the identification and quantification of roxithromycin (ROX) during in vitro skin penetration studies has been developed and validated. The method proved to be simple and rapid ... -
Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites
(Elsevier, 2014)S-adenosyl-L-methionine decarboxylase (AdoMetDC) in the polyamine biosynthesis pathway has been identified as a suitable drug target in Plasmodium falciparum parasites, which causes the most lethal form of malaria. ... -
Novel sulfanylphthalimide analogues as highly potent inhibitors of monoamine oxidase B
(Elsevier, 2012)Monoamine oxidase (MAO) plays an essential role in the catabolism of neurotransmitter amines. The two isoforms of this enzyme, MAO-A and -B, are considered to be drug targets for the therapy of depression and neurodegenerative ... -
NT-proBNP and metabolic risk factors in two ethnic groups: the SABPA cohort study
(Oxford Univ Press, 2018)Background: Natriuretic peptides are vasoactive peptides with several metabolic actions. Purpose: We aimed to explore associations of N-terminal pro-brain natriuretic peptide (NT-proBNP) with metabolic traits in a mixed ... -
NT-proBNP and potential vascular calcification in black and caucasian African men: the SAfrEIC study
(ISHIB, 2012)OBJECTIVE: The N-terminal prohormone B-type natriuretic peptide (NT-proBNP) is a reliable marker of cardiac strain. In hypertensive heart disease, NT-proBNP levels increase and may lose its protective function. Simultaneously, ... -
NT-proBNP is associated with fibulin-1 in Africans: The SAfrEIC study
(Elsevier, 2012)Objectives The N-terminal prohormone B-type natriuretic peptide (NT-proBNP) is involved in the regulation of volume load and secreted when systemic cardiac overload occurs. Fibulin-1 on the other hand is a component of ... -
NT–proBNP, C–reactive protein and soluble uPAR in a Bi–ethnic male population: the SAfrEIC study
(Public Library of Science, 2013)Objective and design: This cross-sectional study aimed to investigate associations between a marker of cardiac strain, the N-terminal prohormone B-type natriuretic peptide (NT-proBNP), and inflammation as reflected by ... -
Nurse qualifications and perceptions of patient safety and quality of care in South Africa
(Wiley, 2014)A plethora of research links professional nurses’ qualifications to patient outcomes. Also, research has shown that reports by nurses on the quality of care correspond with process or outcome measures of quality in a ... -
Nurses' attitudes towards a computerised health information system in a private South African hospital
(Unisa Press, 2020)Various researchers have explored the use of health information systems (HISs) in the public sector in South Africa, including users’ experiences thereof. However, there is limited research relating to the private health ... -
Nurses' engagement in AIDS policy development
(Wiley, 2013)Background: A multidisciplinary team of 20 researchers and research users from six countries – Canada, Jamaica, Barbados, Kenya, Uganda and South Africa – are collaborating on a 5-year (2007–12) program of research and ... -
Nutrient adequacy
(Karger, 2015)Key Messages "Nutrient adequacy, a result of consumption of sufficient amounts of all essential nutrients and energy to meet individual requirements, is a prerequisite for normal growth, development and health. " ... -
Nutrient patterns associated with fasting glucose and glycated haemoglobin levels in a Black South African population
(MDPI, 2017)Type 2 diabetes (T2D) burden is increasing globally. However, evidence regarding nutrient patterns associated with the biomarkers of T2D is limited. This study set out to determine the nutrient patterns associated with ...