Browsing Faculty of Health Sciences by Title
Now showing items 1253-1272 of 2377
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Inulin suitable as reduced-kilojoule carrier for production of microencapsulated spray-dried green Cyclopia subternata (honeybush) extract
(Elsevier, 2017)Retention of phenolic compounds during spray-drying of an anti-diabetic C. subternata extract and physicochemical characteristics of spray-dried powders (pure extract and extract-carrier mixtures) were evaluated. Extract-carrier ... -
Inventory on the dietary assessment tools available and needed in Africa: a prerequisite for setting up a common methodological research infrastructure for nutritional surveillance, research, and prevention of diet-related non-communicable diseases
(Taylor & Francis, 2018)Objective: To carry out an inventory on the availability, challenges, and needs of dietary assessment (DA) methods in Africa as a pre-requisite to provide evidence, and set directions (strategies) for implementing common ... -
Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatium
(Elsevier, 2008)We investigated the protective effect of pravastatin, simvastatin and atorvastatin on striatal DNA damage as a potential method to conserve and protect the nigrostriatal neurons. C57Bl/J6 mice were treated with combinations ... -
Investigating the role of protein kinase-G in the antidepressant-like response of sildenafil in combination with muscarinic acetylcholine receptor antagonism
(Elsevier, 2010)The cGMP/PK-G pathway plays a crucial role in neuroprotection and neurotrophin support, and is possibly involved in antidepressant action. Recently we reported on a novel antidepressant-like response following simultaneous ... -
An investigation into the bioavailability of a peroral cannabinoid-Pheroid® formulation
(Elsevier, 2019)Cannabidiol (CBD), a phytocannabinoid isolated from the Cannabis sativa plant, has been investigated for its medicinal properties including anti-psychotic, anti- emetic, anti-inflammatory, anxiolytic and anti- convulsant ... -
Investigation of the coexistence of CKD and non-communicable chronic diseases in a PBM company in South Africa
(Taylor & Francis, 2016)Background: Chronic kidney disease (CKD) is a public health problem, with increasing global prevalence. Several factors could influence the prognosis of CKD, including comorbid chronic conditions. This study investigated ... -
An investigation of the monoamine oxidase inhibition properties of pyrrolo[3,4‐f]indole‐5,7‐dione and indole‐5,6‐dicarbonitrile derivatives
(Wiley, 2018)In recent studies, we have shown that pyrrolo[3,4‐f]indole‐5,7‐dione and indole‐5,6‐dicarbonitrile derivatives act as good potency in vitro inhibitors of the monoamine oxidase (MAO) enzymes. To expand on these series and ... -
Iodine status and associations with feeding practices and psychomotor milestone development in six-month-old South African infants
(Wiley, 2017)Iodine is important for normal growth and psychomotor development. While infants below 6 months of age receive iodine from breast milk or fortified infant formula, the introduction of complementary foods poses a serious ... -
Iodine status assessment in South African adults according to spot urinary iodine concentrations, prediction equations, and measured 24-h iodine excretion
(MDPI, 2018)The iodine status of populations is conventionally assessed using spot urinary samples to obtain a median urinary iodine concentration (UIC) value, which is assessed against standard reference cut-offs. The assumption that ... -
Iodine status of pregnant women and children age 6 to 12 years feeding from the same food basket in Mopani district, Limpopo province, South Africa
(Medpharm, 2019)Objectives: The aim of the study was to assess the iodine status of pregnant women and children age 6 to 12 years feeding from the same food basket in Mopani District. Design: A cross-sectional study was conducted. Setting: ... -
Iron and a mixture of DHA and EPA supplementation, alone and in combination, affect bioactive lipid signalling and morbidity of iron deficient South African school children in a two-by-two randomised controlled trial
(Elsevier Sci Ltd, 2016)We recently reported that iron supplementation increased respiratory morbidity in iron deficient South African children. This increase, however, was attenuated when iron was provided in combination with a mixture of DHA/EPA. ... -
Iron loading, alcohol and mortality: a prospective study
(Elsevier, 2019)Background & aims The relationship between total body iron and cardiovascular disease remains controversial and information absent in black sub-Saharan Africans in whom alcohol consumption tends to be high. The level of ... -
Iron status and cardiovascular disease risk in black South African women: the PURE study
(MedPharm Publishers, 2011)Objective: To examine the associations between measures of iron status and cardiovascular disease (CVD) risk factors in South African women. Method: In a cross-sectional study, demographic information and health history ... -
Is 24-hour central blood pressure superior to 24-hour brachial blood pressure for predicting organ damage?
(American Heart Association, 2017) -
Is epicardial fat depot associated with atrial fibrillation? A systematic review and meta-analysis
(Oxford Univ Press, 2017)Aims Atrial fibrillation (AF) is the leading rhythm disorder in western countries. A direct relationship between left atrium (LA) enlargement and electromechanical remodelling has been established. A causative link between ... -
Is guideline-driven prophylaxis for venous thromboembolism common practice in the South African private hospital setting?
(AOSIS, 2020)Background: Prophylactic venous thromboembolism (VTE) strategies have the greatest impact on patient outcomes. Both global and local guidelines support VTE prophylaxis for hospitalised patients. However, studies have ... -
Is HIV-1 infection associated with endothelial dysfunction in a population of African ancestry in South Africa?
(Clinics Cardive, 2011)The chronic infection status suffered by HIV-infected individuals promotes chronic arterial inflammation and injury, which leads to dysfunction of the endothelium, atherosclerosis and thrombosis. Although HIV-1 subtype C ... -
Is it worthwhile to flip? Reflecting on flipped teaching in chemical engineering
(CUT, 2016)The flipped classroom approach has been successfully implemented in a wide range of study fields. The use of the flipped classroom as part of a blended learning strategy in chemical engineering, however, is not a ... -
Is major depressive disorder a metabolic encephalopathy?
(Wiley, 2008)Metabolic encephalopathy is an acute disturbance in cellular metabolism in the brain evoked by conditions of hypoxia, hypoglycaemia, oxidative stress and/or inflammation. It usually develops acutely or subacutely and is ... -
Is the cardiovascular health of South Africans today comparable with African Americans 45 years ago?
(Wolters Kluwer, 2019)Objectives: Hypertension occurs frequently among black populations around the world. In the United States (US) health system, interventions since the 1960s resulted in improvements in hypertension awareness, management ...