Browsing Faculty of Health Sciences by Title
Now showing items 1250-1269 of 2385
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Intervention strategies used to address alcohol abuse in the North West Province, South Africa
(Stellenbosch University Library and Information Service, 2015)Alcohol abuse has been reported as a major concern and is a source of social and economic problems in many developing countries such as South Africa (Monteiro, 2001:98; WHO, 2014:1). The Minister of Social Development ... -
Interventions to prevent iron deficiency during the first 1000 days in low-income and middle-income countries: recent advances and challenges
(Wolters Kluwer, 2019)Purpose of review Iron deficiency remains highly prevalent in women and young children in low-income and middle-income countries. To prevent the potentially life-long consequences of iron deficiency when occurring during ... -
Interventions to promote psychiatric patients’ compliance to mental health treatment: a systematic review
(AOSIS, 2014)BACKGROUND: Non-compliance to treatment remains one of the greatest challenges in mental healthcare services, and how to improve this remains a problem. AIM: The aim of this study was to critically synthesise the best ... -
Intestinal drug absorption enhancement by Aloe vera gel and whole leaf extract: in vitro investigations into the mechanisms of action
(MDPI, 2019)The co-administration of absorption enhancing agents with macromolecular drugs (e.g., protein and peptide drugs) has been identified as a means to improve the oral bioavailability of these drugs. Absorption-enhancing agents ... -
Intestinal drug absorption enhancers: synergistic effects of combinations
(Taylor & Francis, 2008)Although many absorption enhancers have been investigated, very few are used clinically. A need exists therefore for more effective absorption enhancers. The drug-absorption-enhancing effects of combinations of N-trimethyl ... -
An introduction to Bayesian statistics in health psychology
(Taylor & Francis, 2017)The aim of the current article is to provide a brief introduction to Bayesian statistics within the field of health psychology. Bayesian methods are increasing in prevalence in applied fields, and they have been shown in ... -
An introduction to the revised food-based dietary guidelines for South Africa
(MedPharm Publications, 2013)Food-based dietary guidelines (FBDGs) are short, positive, science-based messages that aim to change the eating behaviour of the general population towards more optimal diets that meet energy and nutrient requirements, ... -
Inulin as microencapsulating agent improves physicochemical properties of spray-dried aspalathin-rich green rooibos (Aspalathus linearis) extract with α-glucosidase inhibitory activity
(Elsevier, 2018)Limiting aspalathin degradation during spray-drying of green rooibos extract (GRE) is crucial to produce a functional food ingredient with antidiabetic properties. Retention of aspalathin in a GRE-inulin mixture (1:1, m/m) ... -
Inulin suitable as reduced-kilojoule carrier for production of microencapsulated spray-dried green Cyclopia subternata (honeybush) extract
(Elsevier, 2017)Retention of phenolic compounds during spray-drying of an anti-diabetic C. subternata extract and physicochemical characteristics of spray-dried powders (pure extract and extract-carrier mixtures) were evaluated. Extract-carrier ... -
Inventory on the dietary assessment tools available and needed in Africa: a prerequisite for setting up a common methodological research infrastructure for nutritional surveillance, research, and prevention of diet-related non-communicable diseases
(Taylor & Francis, 2018)Objective: To carry out an inventory on the availability, challenges, and needs of dietary assessment (DA) methods in Africa as a pre-requisite to provide evidence, and set directions (strategies) for implementing common ... -
Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatium
(Elsevier, 2008)We investigated the protective effect of pravastatin, simvastatin and atorvastatin on striatal DNA damage as a potential method to conserve and protect the nigrostriatal neurons. C57Bl/J6 mice were treated with combinations ... -
Investigating the role of protein kinase-G in the antidepressant-like response of sildenafil in combination with muscarinic acetylcholine receptor antagonism
(Elsevier, 2010)The cGMP/PK-G pathway plays a crucial role in neuroprotection and neurotrophin support, and is possibly involved in antidepressant action. Recently we reported on a novel antidepressant-like response following simultaneous ... -
An investigation into the bioavailability of a peroral cannabinoid-Pheroid® formulation
(Elsevier, 2019)Cannabidiol (CBD), a phytocannabinoid isolated from the Cannabis sativa plant, has been investigated for its medicinal properties including anti-psychotic, anti- emetic, anti-inflammatory, anxiolytic and anti- convulsant ... -
Investigation of the coexistence of CKD and non-communicable chronic diseases in a PBM company in South Africa
(Taylor & Francis, 2016)Background: Chronic kidney disease (CKD) is a public health problem, with increasing global prevalence. Several factors could influence the prognosis of CKD, including comorbid chronic conditions. This study investigated ... -
An investigation of the monoamine oxidase inhibition properties of pyrrolo[3,4‐f]indole‐5,7‐dione and indole‐5,6‐dicarbonitrile derivatives
(Wiley, 2018)In recent studies, we have shown that pyrrolo[3,4‐f]indole‐5,7‐dione and indole‐5,6‐dicarbonitrile derivatives act as good potency in vitro inhibitors of the monoamine oxidase (MAO) enzymes. To expand on these series and ... -
Iodine status and associations with feeding practices and psychomotor milestone development in six-month-old South African infants
(Wiley, 2017)Iodine is important for normal growth and psychomotor development. While infants below 6 months of age receive iodine from breast milk or fortified infant formula, the introduction of complementary foods poses a serious ... -
Iodine status assessment in South African adults according to spot urinary iodine concentrations, prediction equations, and measured 24-h iodine excretion
(MDPI, 2018)The iodine status of populations is conventionally assessed using spot urinary samples to obtain a median urinary iodine concentration (UIC) value, which is assessed against standard reference cut-offs. The assumption that ... -
Iodine status of pregnant women and children age 6 to 12 years feeding from the same food basket in Mopani district, Limpopo province, South Africa
(Medpharm, 2019)Objectives: The aim of the study was to assess the iodine status of pregnant women and children age 6 to 12 years feeding from the same food basket in Mopani District. Design: A cross-sectional study was conducted. Setting: ... -
Iron and a mixture of DHA and EPA supplementation, alone and in combination, affect bioactive lipid signalling and morbidity of iron deficient South African school children in a two-by-two randomised controlled trial
(Elsevier Sci Ltd, 2016)We recently reported that iron supplementation increased respiratory morbidity in iron deficient South African children. This increase, however, was attenuated when iron was provided in combination with a mixture of DHA/EPA. ... -
Iron loading, alcohol and mortality: a prospective study
(Elsevier, 2019)Background & aims The relationship between total body iron and cardiovascular disease remains controversial and information absent in black sub-Saharan Africans in whom alcohol consumption tends to be high. The level of ...