Now showing items 1-2 of 2

    • An evaluation of synthetic indole derivatives as inhibitors of monoamine oxidase 

      Chirkova, Zhanna V.; Petzer, Anél; Petzer, Jacobus P.; Kabanova, Mariya V.; Filimonov, Sergey I. (Elsevier, 2016)
      In a recent study we have shown that several indole-5,6-dicarbonitrile derivatives are potent inhibitors of human monoamine oxidase (MAO) A and B. To expand on these results and to further determine structure–activity ...
    • Inhibition of monoamine oxidase by indole-5,6-dicarbonitrile derivatives 

      Chirkova, Zhanna V.; Petzer, Anél; Petzer, Jacobus P.; Kabanova, Mariya V.; Filimonov, Sergey I. (Elsevier, 2015)
      Recent studies have found that phthalonitrile derivatives are remarkably potent inhibitors of human monoamine oxidase (MAO) A and B. In an attempt to further determine the structure-activity relationships (SARs) for MAO ...