Browsing Conference Papers - Potchefstroom Campus by Author "4ba68534-d01e-4573-bd82-64c82f493108"

Now showing items 1-3 of 3

    • The effect of entrapment of a peptide in Pheroid® on pharmacokinetics and testosterone levels 

      Hayeshi, Rose; Erasmus, Linné; Scholtz, Liezl-Marie; Venter, Kobus; Bester, Cor; Fick, Antoinette; Leussa, Nyango-Nkeh Adrienne; Grobler, Anne (Elsevier, 2019)
      Goserelin is a peptide drug that suppresses levels of testosterone and oestradiol [1]. The current formulation is presented in a sustained-release depot with several approved indications such as treatment of endometriosis, ...

    • Evaluation of the oral delivery of a peptide with Pheroid® technology 

      Erasmus, Linné; Scholtz, Liezl-Marie; Venter, Kobus; Bester, Cor; Fick, Antoinette; Mabena, Jacob; Grobler, Anne; Hayeshi, Rose (Elsevier, 2019)
      Goserelin is a type of hormone therapy used in addition to standard adjuvant therapy. Currently, goserelin is only available as a slow releasing subcutaneous implant but this is an invasive and generally not well- tolerated ...

    • An investigation into the bioavailability of a peroral cannabinoid-Pheroid® formulation 

      Erasmus, Stephanie; Cloete, Theunis; Scholtz, Liezl-Marie; Grobler, Anne F.; Magwasa, Martin S. (Elsevier, 2019)
      Cannabidiol (CBD), a phytocannabinoid isolated from the Cannabis sativa plant, has been investigated for its medicinal properties including anti-psychotic, anti- emetic, anti-inflammatory, anxiolytic and anti- convulsant ...