Browsing by Subject "Solid-state"
Now showing items 1-3 of 3
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Artesunate - An investigation into polymorphism
(North-West University (South-Africa), 2020)Artesunate (ART) is a derivative of artemisinin and is used in the treatment of uncomplicated Plasmodium falciparum (P. falciparum) malaria. Limited and unreliable solid-state and physico-chemical data is currently available ... -
Rifampicin raw materials complexities and approaches to address solubility and in vitro permeability
(North-West University (South-Africa), 2021)Tuberculosis is classified as a global emergency because it is taking lives at an alarming rate and developing countries with insufficient health care systems are primarily affected. Fixed dose combination drugs (FDCs) ... -
Water and the relationship to the crystal structure stability of azithromycin: thermal investigations of solvatomorphism, amorphism and polymorphism
(Springer, 2018)This study investigated the solid-state physical stabilities of azithromycin dihydrate (AZM-DH), thermally prepared anhydrate and hemihydrate modifications. Programmed thermal treatment of AZM-DH in DSC yielded the formation ...