Browsing by Subject "Skin permeation"

Now showing items 1-6 of 6

    • In vitro permeation of platinum and rhodium through Caucasian skin 

      Franken, A.; Eloff, F.C.; Du Plessis, J.; Badenhorst, C.J.; Jordaan, A.; Du Plessis, J.L. (Elsevier, 2014)
      During platinum group metals (PGMs) refining the possibility exists for dermal exposure to PGM salts. The dermal route has been questioned as an alternative route of exposure that could contribute to employee sensitisation, ...

    • In vitro skin permeation of artemisone and its nano-vesicular formulations 

      Dwivedi, Anupma; Mazumder, Anisha; Fox, Lizelle T.; Brümmer, Alicia; Gerber, Minja; Du Preez, Jan L.; Haynes, Richard K.; Du Plessis, Jeanetta (Elsevier, 2016)
      The artemisinin derivative artemisone has antitumor activity. In particular when encapsulated in solid lipid nanoparticles (SLNs) and niosomes, it is active against human melanoma A-375 cells, although such formulations ...

    • In vitro skin permeation of sinigrin from its phytosome complex 

      Mazumder, Anisha; Dwivedi, Anupma; Fox, Lizelle T.; Brümmer, Alicia; Du Preez, Jan L.; Gerber, Minja; Du Plessis, Jeanetta (Wiley, 2016)
      Objectives: Sinigrin is a major glucosinolate present in plants of the Brassicaceae family. Recently sinigrin and its phytosome formulations have been investigated for its wound healing actions, by our research group. The ...

    • The influence of pH on the in vitro permeation of platinum through human skin 

      Van Nieuwenhuizen, Yolandi (North-West University (South Africa) , Potchefstroom Campus, 2016)
      Background: At platinum mines and refineries, and other industries such as the catalytic industry, workers are at risk of being potentially exposed via dermal contact to soluble platinum salts, which are known sensitisers ...

    • Reflections on the OECD guidelines for in vitro skin absorption studies 

      Hopf, N.B.; Du Plessis, J.L.; Franken, A.; Frasch, F.; Champmartin, C.; Schenk, L.; Berthet, A.; Chedik, L.; Gaskin, S. (Elsevier, 2020)
      At the 8th conference of Occupational and Environmental Exposure of the Skin to Chemicals (OEESC) (16–18 September 2019) in Dublin, Ireland, several researchers performing skin permeation assays convened to discuss in vitro ...

    • Transport of aspalathin, a rooibos tea flavonoid, across the skin and intestinal epithelium 

      Huang, Miao; Du Plessis, Jeanetta; Du Preez, Jan; Hamman, Josias; Viljoen, Alvaro (Wiley, 2008)
      Since Rooibos tea contains high levels of flavonoid antioxidants with potential health benefits when taken orally or applied topically, the quantity of the antioxidants crossing the physiological barriers is of scientific, ...