Browsing by Subject "SNP"
Now showing items 1-3 of 3
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Characterisation of the influence of genetic variations on the enzyme activity of a recombinant human glycine N-acyltransferase
(Elsevier, 2013)Human glycine N-acyltransferase (human GLYAT) detoxifies a wide range of endogenous and xenobiotic metabolites, including benzoate and salicylate. Significant inter-individual variation exists in glycine conjugation capacity. ... -
Investigation and characterisation of the genetic variation in the coding region of the glycine N-acyltransferase gene
(North-West University, 2015)Thorough investigation of the glycine conjugation pathway has been neglected over the last 30 years. Environmental factors, nutrition, and the chronic use of medications are increasing the exposure of humans to benzoate ... -
Sequencing and molecular characterization of variations in the glycine N–acyltransferase gene
(2014)Humans are continuously challenged by harmful endogenous and xenobiotic substances. Detoxification is the ability to neutralise and remove these substances from the body. Glycine N-acyltransferase, EC 2.3.1.13 (GLYAT) is ...