Browsing by Subject "Partition coefficient"
Now showing items 1-2 of 2
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Percutaneous absorption of cyclizine and its alkyl analogues
(North-West University, 2003)Percutaneous delivery of drugs promises many advantages over oral or intravenous administration, such as a better control of blood levels, a reduced incidence of systemic toxicity, an absence of hepatic first-pass ... -
Percutaneous delivery of thalidomide and its N-alkyl analogues for treatment of rheumatoid arthritis
(Potchefstroom University for Christian Higher Education, 1998)Rheumatoid arthritis (RA) is a chronic inflammatory joint disease associated with high levels of tumour necrosis factor-alpha (TNF-a) in synovial fluid and synovial tissue (Saxne et al., 1989). Thalidomide is a proven ...