Now showing items 1-7 of 7

    • Formulation and topical delivery of niosomes and proniosomes containing carnosine 

      Lundie, Martha Maria (North-West University (South Africa) , Potchefstroom Campus, 2016)
      Wiechers (2008:1-18) explains that the efficacy of a biologically active cosmetic product depends on both the intrinsic activity of the active, as well as the delivery of the active. This study aimed to deliver the ...
    • Formulation of an emulgel for topical delivery of roxithromycin 

      Steenkamp, Vernice (North-West University (South-Africa), 2020)
      The aim of this study was to establish whether liposomal or niosomal vesicle systems containing roxithromycin could be developed further into semi-solid formulations (emulgels) for topical delivery of the active pharmaceutical ...
    • In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells 

      Dwivedi, Anupma; Mazumder, Anisha; Du Plessis, Lissinda; Du Preez, Jan L.; Haynes, Richard K.; Du Plessis, Jeanetta (Elsevier, 2015)
      Artemisone is a 10-amino-artemisinin derivative that is markedly superior in vitro and in vivo to current artemisinins against malaria and also possesses antitumor activity. In seeking to capitalise on the last property, ...
    • In vitro skin permeation of artemisone and its nano-vesicular formulations 

      Dwivedi, Anupma; Mazumder, Anisha; Fox, Lizelle T.; Brümmer, Alicia; Gerber, Minja; Du Preez, Jan L.; Haynes, Richard K.; Du Plessis, Jeanetta (Elsevier, 2016)
      The artemisinin derivative artemisone has antitumor activity. In particular when encapsulated in solid lipid nanoparticles (SLNs) and niosomes, it is active against human melanoma A-375 cells, although such formulations ...
    • Investigation of the stabilising effects of niosomes on the amorphous forms of roxithromycin 

      Boshoff, Suné (North-West University (South Africa), Potchefstroom Campus, 2018)
      The first aim of this research study was to determine the effect of the excipients used in the typical niosome preparation on the solid-state nature of three solid-state forms of roxithromycin. The second aim was to ascertain ...
    • Topical delivery of clofazimine, artemisone and decoquinate utilizing vesicles as carrier system 

      Van Zyl, Lindi (North-West University (South Africa), Potchefstroom Campus, 2018)
      Artemisone, clofazimine and decoquinate are part of the MALTBRedox MRC South African University Flagship Projects, which focus on oxidant-redox drug combinations for the treatment of tuberculosis and a few other diseases. ...
    • Topical delivery of Withania somnifera crude extracts in niosomes and solid lipid nanoparticles 

      Chinembiri, Tawona N.; Gerber, Minja; Du Plessis, Lissinda H.; Du Preez, Jan L.; Hamman, Josias H.; Du Plessis, Jeanetta (Medknow, 2017)
      Background: Withania somnifera is a medicinal plant native to India and is known to have anticancer properties. It has been investigated for its anti-melanoma properties, and since melanoma presents on the skin, it is ...