Browsing by Subject "Nanoparticle drug delivery"

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Functionalization of PLGA nanoparticles with 1,3-β-glucan enhances the intracellular pharmacokinetics of rifampicin in macrophages

Tukulula, Matshawandile; Hayeshi, Rose; Gouveia, Luis; Paixao, Paulo; Naicker, Brendon (Springer, 2018)

Purpose Mycobacterium tuberculosis which causes tuberculosis, is primarily resident within macrophages. 1,3-β-glucan has been proposed as a ligand to target drug loaded nanoparticles (NPs) to macrophages. In this study ...