Browsing by Subject "Molecular hybridization"
Now showing items 1-3 of 3
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Nitrothiazole-thiazolidinone hybrids : synthesis and in vitro antimicrobial evaluation
(North-West University (South-Africa), 2023)Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis (Mtb), is one of the world’s most fatal infectious diseases. Annually, 10 million people fall ill with TB and 1.5 million people die from it globally. ... -
Synthesis and in vitro antimycobacterial and antileishmanial activities of hydroquinone-triazole hybrids
(Springer, 2020)Infectious diseases such as tuberculosis and leishmaniasis are leading causes of human death. One of the major factors contributing to the poor control of these diseases is primarily the reduced effectiveness of the existing ... -
Synthesis and in vitro Leishmania promastigote growth inhibition efficacy of novel 4(3H)-quinazolinone derivatives
(ARKAT USA, 2020)Molecular hybridization is an increasingly important strategy in rational drug design and development. A series of novel quinazolinone-triazole hybrids have been synthesized and their antileishmanial activity investigat ...