Browsing by Subject "Gold nanoparticles"
Now showing items 1-9 of 9
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An assessment of the biodistribution, biopersistence and toxicity of gold nanoparticles
(North-West University (South Africa) , Potchefstroom Campus, 2015)The interest in biomedical applications of gold nanoparticles (AuNPs) has increased dramatically in the last decade due to their ease of synthesis, unique surface and optical properties. The main driver of this surge in ... -
Bioaccumulation and subchronic toxicity of 14 nm gold nanoparticles in rats
(MDPI, 2016)Colloidal suspensions of 14 nm gold nanoparticles (AuNPs) were repeatedly administered intravenously at three dose levels (0.9, 9 and 90 µg) to male Sprague Dawley rats weekly for 7 weeks, followed by a 14-day washout ... -
Development and optimisation of gold nanoparticle based bioassays
(North-West University (South Africa). Potchefstroom Campus, 2019)Gold nanoparticles, in particular nanostars, are being utilised more regularly in the field of biosensing. Despite their useful attributes, there is still a need to optimise aspects of the synthesis and stability of the ... -
Dual radiolabeling as a technique to track nanocarriers: the case of gold nanoparticles
(MDPI, 2015)Gold nanoparticles (AuNPs) have shown great potential for use in nanomedicine and nanotechnologies due to their ease of synthesis and functionalization. However, their apparent biocompatibility and biodistribution is still ... -
The genotoxic effect of gold nanoparticles in cultured human cells
(North-West University (South Africa), 2016)Gold nanoparticles are ultrafine particles which are being used diversely in the medical field. Despite their versatility, the toxicity research which has been conducted on these particles is incredibly limited as well ... -
Metabolic variation in cultured cells treated with differentially functionalised gold nanoparticles (GNPs)
(North-West University (South Africa), Potchefstroom Campus, 2017)Gold nanoparticles (GNPs) and differentially functionalised or ligand exchanged GNPs (Lig-GNPs) present promising advantages in a variety of fields. Surface functionalisation of GNPs with ligands is believed to improve the ... -
A metabolomics investigation of a nanogold drug vehicle on experimental animals
(North-West University (South Africa), 2019-05)Nanotechnology has increasingly received attention the last few decades and the term refers to the categories of applied science and technology, where the combining key subject is the study of matter in scales of 1 to 100 ... -
Metabolomics reveals the depletion of intracellular metabolites in HepG2 cells after treatment with gold nanoparticles
(Taylor & Francis, 2018)Studies on the safety of gold nanoparticles (GNPs) are plentiful due to their successful application in drug delivery and treatment of diseases in trials. Cytotoxicity caused by GNPs has been studied on the physiological ... -
Transforming diatomaceous earth into sensing devices by surface modification with gold nanoparticles
(Elsevier, 2019)Diatomaceous earth, or diatomite, is produced through the accumulation of diatom (Bacillariophyceae) skeletons(i.e. cell walls called frustules) made of amorphous silica. The porous, highly symmetrical structure and ...
