Browsing by Subject "Glucocerebrosidase"
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Advances in GBA-associated Parkinson's disease: pathology, presentation and therapies
(Elsevier, 2016)GBA mutations are to date the most common genetic risk factor for Parkinson's disease. The GBA gene encodes the lysomal hydrolase glucocerebrosidase. Whilst bi-allelic GBA mutations cause Gaucher disease, both mono- and ... -
A molecular analysis of the GBA gene in Caucasian South Africans with Parkinson's disease
(Wiley, 2017)Background The molecular basis of Parkinson's disease in South African population groups remains elusive. To date, substitutions in the GBA gene are the most common large-effect genetic risk factor for Parkinson's disease. ...