Browsing by Subject "Gametocytocidal activity"

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Antimalarial N-1,N-3-dialkyldioxonaphthoimidazoliums: synthesis, biological activity, and structure-activity relationships

Ahenkorah, Stephen; Haynes, Richard; Coertzen, Dina; Tong, Jie Xin; Fridianto, Kevin (ACS, 2020)

Here we report the nanomolar potencies of N1,N3-dialkyldioxonaphthoimidazoliums against asexual forms of sensitive and resistant Plasmodium falciparum. Activity was dependent on the presence of the fused quinone-imidazolium ...