Browsing by Subject "Epac"

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An inhibitor of cAMP-dependent protein kinase induces behavioural and neurological antidepressant-like effects in rats

Liebenberg, Nico; Harvey, Brian Herbert; Brink, Christiaan B.; Müller, Heidi Kaastrup; Fischer, Christina Weide (Elsevier, 2011)

Although it is well established that cyclic adenosine monophosphate (cAMP) signalling via cAMPdependent protein kinase (PKA)within neurons plays an important role in depression and antidepressant treatment, the importance ...