Browsing by Subject "DprE1 enzyme"

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    • 6-Nitro-1-benzylquinolones exhibiting specific antitubercular activity 

      Beteck, Richard M.; Van der Kooy, Frank; Legoabe, Lesetja J.; Jordaan, Audrey; Swart, Tarryn (Wiley, 2020)
      In this study, we synthesized novel nitro quinolone‐based compounds and tested them in vitro against a panel of Gram‐positive and Gram‐negative pathogens including Mycobacterium tuberculosis (MTB), Pseudomonas aeruginosa ...