Browsing by Subject "Depressie"
Now showing items 1-10 of 10
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Depressed, not depressed or unsure : prevalence and the relation to well–being across sectors in South Africa
(2011)Depression is one of the most debilitating, widespread and costly health problems worldwide and has a high prevalence in almost every society. Research suggests that depression affects an individual's work engagement levels, ... -
Early-life exposure to fluoxetine and/or exercise on bio-behavioural markers of depression in early adulthood in stress sensitive rats
(North-West University (South Africa) , Potchefstroom Campus, 2015)Juvenile depression is a major concern worldwide, with only the selective serotonin reuptake inhibitors (SSRIs) fluoxetine and escitalopram approved for treatment. The effects of early-life exposure to SSRIs on neurodevelopment ... -
The effect of early–life exposure of rats to venlafaxine on behaviour and neurological markers of antidepressant action in adulthood
(2014)Major depression is a serious mood disorder affecting more than 120 million people worldwide, irrespective of their race or socio-economic status. This psychiatric disorder is predicted to become the second leading cause ... -
Endogenous markers of nitric oxide in the Flinders sensitive line (FSL) rat : a genetic animal model of depression
(North-West University, 2010)The rising number of the population that present with major depressive disorder has intensified the need to identify and elucidate new biological markers for the diagnosis and treatment of depression. Depression presents ... -
Investigating discriminant validity and explained variance of burnout, depressive symptoms, job demands and satisfaction with life
(North-West University (South Africa). Potchefstroom Campus, 2016)Burnout is accepted as a work-related phenomenon that impacts negatively on individuals and organisations. However, the conceptualisation of burnout is contested. Recent research challenge the distinction drawn between ... -
The long-term effects of fluoxetine on stress-related behaviour and acute monoaminergic stress response in stress sensitive rats
(2014)Fluoxetine and escitalopram are the only antidepressants approved by the Food and Drug Administration of the United States of America (FDA) for treatment of major depression in children and adolescents. Both drugs are ... -
The long-term effects of methamphetamine on depressive-like behaviour and neuroplasticity in stress-sensitive rats
(2014)Methamphetamine (METH) abuse has become a fast growing drug problem that has developed into a global epidemic. In fact, METH is one of the most commonly abused substances with an estimated 35 million abusers worldwide and ... -
The relationship between coping strategies and depression in an African context
(North-West University, 2011)Depression is a psychiatric disorder associated with severe impairment in physical, social and role functioning, and with higher health care utilization. Experiencing an event that causes physical or psychological stress ... -
Role–specific stress, physical and psychological health and social support in a mining training academy
(North-West University, 2011)The mining industry in South Africa plays a significant role in the economy of the country. South Africa is rated as one of the world’s largest producers of key reserves - gold, manganese ore and platinum– and the high ... -
Validation of the Patient Health Questionnaire (PHQ–9) in an African context
(North-West University, 2011)This research was aimed at validating the PHQ–9 in an African context. This study forms part of the project of Psychosocial Health and Biomarkers in an African context (FORT3, Wissing, 2008). The Patient Health Questionnaire ...
