Browsing by Subject "DNA sequencing"
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An analysis of the effect of transformation on global– and gene–specific DNA methylation in four cultured cell lines
(North-West University, 2010)DNA methylation plays a role in several biological functions, such as gene expression regulation, and several endogenous and exogenous factors affect these DNA methylation patterns in the cell. One such alteration of a ... -
Is the role of circulating DNA as a biomarker of cancer being prematurely overrated?
(Elsevier, 2010)Background Circulating DNA is utilized widely as a genetic biomarker in a variety of pathological conditions, mainly in cancerous conditions. Quantification of circulating DNA and identifying the frequencies of a variety ...