Browsing by Subject "Chloroquine"
Now showing items 1-5 of 5
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Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration
(Oxford Univ Press, 2019)Objectives Drug resistance exists to all current and investigational antimalarial drug classes. Consequently, we have set out to develop chemically and mechanistically discrete antimalarials. Here we report on the development ... -
Evaluation and validation of methods to determine parasitemia in malaria cell cultures
(North-West University, 2008)The success in the treatment of malaria is dependent on the prompt and accurate diagnosis of malaria and effectiveness of the drug regime used. The emerging of resistance to most antimalarial drug makes the treatment of ... -
Preclinical evaluation of the possible enhancement of the efficacy of anti-malarial drugs by pheroid technology
(North-West University, 2007)Malaria is currently one of the most imperative parasitic diseases of the developing world. Current effective treatment options are limited because of increasing drug resistance, treatment cost effectiveness and treatment ... -
Synthesis and antimalarial activity of ethylene glycol oligomeric ethers of artemisinin
(Wiley, 2011)Objectives The aim of this study was to synthesize a series of ethylene glycol ether derivatives of the antimalarial drug artemisinin, determine their values for selected physicochemical properties and evaluate their ... -
Synthesis and antimalarial activity of ethylene glycol oligomeric ethers of artemisinin
(Wiley, 2011)Objectives The aim of this study was to synthesize a series of ethylene glycol ether derivatives of the antimalarial drug artemisinin, determine their values for selected physicochemical properties and evaluate their ...
