Now showing items 1-3 of 3

    • Biocatalytic resolution of substituted styrene oxides 

      Yeates, Charl Alan (Potchefstroom University for Christian Higher Education, 2001)
      Stereochemistry and chirality are arguably two of the most important subjects pertaining to the development of new pharmaceutical drugs. Since enantiomers have the potential to encompass different pharmacological effects ...
    • Optimisation of conditions for the resolution of 1,2-epoxyoctane in a bioreactor 

      Le Roux, Ilani (North-West University, 2003)
      Due to recent legislation requiring the determining of the pharmacokinetic effect of both enantiomers separately, of any new racemic drug before commercialisation, much research is done to improve and optimise methods for ...
    • Red yeast epoxide hydrolases : growth, activity and selectivity 

      Maritz, Jana (North-West University, 2007)
      Enantiopure epoxides are versatile compounds in the production of single enantiomer drugs, and are of high value as building blocks and intermediates in the preparation of more complex single enantiomer pharmaceuticals and ...