Browsing by Subject "Atropine"
Now showing items 1-2 of 2
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Investigating the role of protein kinase-G in the antidepressant-like response of sildenafil in combination with muscarinic acetylcholine receptor antagonism
(Elsevier, 2010)The cGMP/PK-G pathway plays a crucial role in neuroprotection and neurotrophin support, and is possibly involved in antidepressant action. Recently we reported on a novel antidepressant-like response following simultaneous ... -
The modulatory effects of sildenafil and the cholinergic system on antidepressant action in a rat model of depression
(North-West University, 2006)Sildenafil, a selective phosphodiesterase type 5 (PDE5) inhibitor, is registered for the treatment of male erectile dysfunction (Viagra®) and pulmonary hypertension (Revatio®) in the United States. PDE5 is found in the ...