Browsing by Subject "Artemether"
Now showing items 1-9 of 9
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Antimalarial activity of 10-alkyl/aryl esters and – aminoethylethers of artemisinin
(Elsevier, 2013)A series of n-alkyl/aryl esters were synthesized and their in vitro antiplasmodial activity was measured alongside that of previously synthesized aminoethylethers of artemisinin ozonides against various strains of ... -
Characterization of solid lipid dispersions prepared by hot fusion containing a double-fixed dose combination of artemether and lumefantrine
(Taylor & Francis, 2020)bjective The World Health Organization has called for the development of novel drug delivery systems to combat malaria – the fourth most prevalent cause of death globally. The plausibility of utilizing hot fusion to prepare ... -
Development and evaluation of a self-emulsifying drug delivery system for artemether and lumefantrine
(North-West University (South-Africa), 2019)Malaria is a grave concern globally, however, in sub-Saharan Africa it remains an even more severe problem due to the fact that more than 90% of all malaria cases caused by Plasmodium falciparum reside in this region. The ... -
Development of lipid matrix tablets containing a double-fixed dose combination of artemether and lumefantrine
(North-West University (South-Africa), 2019)Malaria remains one of the most serious vector-borne and prominent life-threatening diseases in sub-Saharan Africa. Africa has the heaviest malarial disease burden in the world, accounting for 91% of the estimated 445 000 ... -
Formulation and topical delivery of a safflower oil nano-emulsion containing artemether
(North-West University (South Africa) , Potchefstroom Campus, 2016)Cutaneous tuberculosis (CTB), one of the forms of extra-pulmonary tuberculosis (TB), occurs 1.5% of the time when the Mycobacterium tuberculosis bacterium enters the skin, either through direct contact or through airborne ... -
Preclinical evaluation of the possible enhancement of the efficacy of anti-malarial drugs by pheroid technology
(North-West University, 2007)Malaria is currently one of the most imperative parasitic diseases of the developing world. Current effective treatment options are limited because of increasing drug resistance, treatment cost effectiveness and treatment ... -
Synthesis and antimalarial activity of ethylene glycol oligomeric ethers of artemisinin
(Wiley, 2011)Objectives The aim of this study was to synthesize a series of ethylene glycol ether derivatives of the antimalarial drug artemisinin, determine their values for selected physicochemical properties and evaluate their ... -
Synthesis and antimalarial activity of ethylene glycol oligomeric ethers of artemisinin
(Wiley, 2011)Objectives The aim of this study was to synthesize a series of ethylene glycol ether derivatives of the antimalarial drug artemisinin, determine their values for selected physicochemical properties and evaluate their ... -
Topical delivery of artemether, encapsulated in niosome and proniosome carriers
(North-West University (South Africa) , Potchefstroom Campus, 2016)Artemisia annua is a Chinese herb discovered by Chinese scientists in 1971. Artemisinin was extracted from this herb and used as a Chinese medicine named Qinghaosu. Artemether (ARM) is a derivative from the artemisinin ...